Etomidate ISRCTN10813814 Clinical Landscape 2026

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This Clinical Landscape Report was built with PatSnap Life Sciences MCP workflows. Clinical Trials MCP supplies protocol and result records, Drug & Asset MCP adds asset context, and Company & Deal Intelligence MCP resolves sponsor background. Use the same structured MCP building blocks in your research workflow.

Data snapshot: 18 September 2026. This strategic research report is not medical, regulatory or investment advice. Trial status and dates can change.

Not Applicable

Clinical phase

No longer recruiting

Recruitment status

90

Planned enrollment

2023-09-30

Primary-completion proxy

Executive view

ISRCTN10813814 evaluates Etomidate in Ovarian Cancer. The disclosed sponsor is Sponsor not reported, the design is Interventional, and the geographic footprint is China. The first listed primary endpoint is Primary endpoint not reported, assessed over Time frame not reported.

The key landscape question is whether this protocol can generate a clinically interpretable signal relative to nearby programs. Phase alone is not a measure of evidence quality. Endpoint relevance, comparator choice, masking, enrollment feasibility, patient selection, country coverage and follow-up must be considered together.

PatSnap MCP Servers make this assessment reproducible by keeping protocol facts, result evidence, asset attributes and sponsor identity in separate structured calls.

How the MCP evidence stack was assembled

Clinical Trials MCP clinical_trial_fetch retrieved the design, outcomes, phase, status, enrollment, sponsor, countries and timing for ISRCTN10813814 and selected peers. clinical_trial_result_fetch supplied detailed result records from the wider Ovarian Cancer landscape. Drug & Asset MCP drug_fetch was queried for Etomidate, while Company & Deal Intelligence MCP organization_fetch was queried for Sponsor not reported.

This separation reduces a common diligence error: treating a registry label, a company description or a result excerpt as if each represented the complete evidence package. Explore the source workflow at the PatSnap MCP marketplace.

Trial landscape table

Trial	Asset / intervention	Phase / status	Sponsor	Geography	Primary endpoint	Readout proxy
ISRCTN10813814	Etomidate	Not Applicable / No longer recruiting	Sponsor not reported	China	Primary endpoint not reported Time frame not reported	2023-09-30
NCT07651124	Nolgileucel	Not Applicable / Recruiting	CHA University	South Korea	Evaluation of cytotoxicity of cells against cancer cells Treatment period- 2 months, follow-up- 4 months after completion of t…	2026-12-31
NCT07648940	Doxorubicin Hydrochloride	Phase 1 / Completed	Zodiac Produtos Farmacêuticos SA	Brazil	Cmax for liposome encapsulated doxorubicin Up to 336 hours after drug administration	2023-06-22
NCT07634094	Albumin-Bound Paclitaxel	Phase 2 / Not yet recruiting	Sponsor not reported	United States	Dose Limiting Toxicities (DLT) Up to 2 months	2028-08-01
NCT07613723	ZI-MA4-1	Phase 1 / Recruiting	Zelluna Immunotherapy AS	United Kingdom	Safety and tolerability of ZI-MA4-1 From baseline through end of study visit (up to 5 years)	2028-12-01

The table aligns endpoints, sponsors, phases, geographies and readout proxies. It is descriptive, not a head-to-head efficacy comparison. Differences in population, baseline risk, intervention schedule and follow-up can dominate apparent cross-trial differences.

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Protocol design and endpoint interpretation

ISRCTN10813814 is a Not Applicable, no longer recruiting study with 90 planned participants. Allocation is Randomized controlled trial, masking is Open (masking not used), and the intervention model is not reported.

The primary endpoint is “Primary endpoint not reported” over “Time frame not reported.” No additional primary-endpoint description was returned in the selected field set.

Interpretation should test whether the endpoint captures a clinically meaningful change, whether its time horizon matches the proposed biology, and whether treatment discontinuation or missing data can bias the estimate. The planned enrollment of 90 should be assessed against expected effect size, event frequency, multiplicity, subgroup plans and attrition.

No named control drug was returned in the protocol field set. A placebo comparator can strengthen internal efficacy assessment, while an active comparator may better test clinical differentiation. Single-arm and open-label programs require greater weight on objective outcomes, independent assessment and external benchmarks.

Indexed readouts in the surrounding landscape

5 recent result records were selected as contextual evidence for Ovarian Cancer. These records do not establish direct evidence for ISRCTN10813814 unless the registration number matches.

Dynamic circulating tumor DNA (ctDNA) kinetics refine static HRD profiling to predict PARP inhibitor resistance in high-grade serous ovarian cancer (HGSOC)

Not Applicable; n=145; EMR = 68.0 % Source: https://cslide.ctimeetingtech.com/map2026/attendee/confcal/presentation?q=26P

A Phase I/Ib Trial of the CDK4/6 Antagonist Ribociclib And The HDAC Inhibitor Belinostat In Patients With Metastatic Triple Negative Breast Cancer And Recurrent Ovarian Cancer Wit…

Phase 1; n=12; Rate of Dose Limiting Toxicity (DLT) = 1 Participants ; Rate of Dose Limiting Toxicity (DLT) = 2 Participants Source: https://clinicaltrials.gov/ct2/show/results/NCT04315233

A phase II study of androgen receptor inhibition by darolutamide in combination with leuprolide acetate and exemestane in recurrent adult-type ovarian granulosa cell tumor

Phase 2; n=17; ORR = 6.25 % Source: https://pubmed-ncbi-nlm-nih-gov.libproxy1.nus.edu.sg/42574969/

Result fields should be reconciled with the source record before quantitative comparison. Population definitions, analysis sets, dose cohorts, estimands, confidence intervals, rescue therapy and follow-up can materially change the meaning of a numerical endpoint. Clinical Trials MCP supports repeatable refreshes as result records change.

Asset and sponsor context

Etomidate is indexed as Small molecule drug with GABAA receptor biology and a global stage of Approved. The asset profile lists Hospira, Inc. as an originator or developer.

No exact Company & Deal Intelligence profile was returned for Sponsor not reported. Sponsor identity is retained from the trial protocol without adding unsupported corporate claims.

For execution diligence, monitor sponsor ownership, collaborator additions, site expansion, protocol amendments and enrollment revisions. A change in ownership or geography can alter operational confidence as well as the commercial meaning of a future readout.

Development white space

Endpoint white space. Determine whether a more patient-relevant outcome, longer durability window or blinded central assessment would resolve uncertainty left by the current endpoint.
Population white space. Test biomarker-defined, treatment-line or risk-stratified subgroups where effect size and unmet need could be clearer.
Comparator white space. Identify whether the study can support differentiation against the current standard of care rather than only activity against baseline or placebo.
Geographic white space. Assess whether the disclosed footprint supports recruitment, regulatory transferability and commercial generalizability.
Sequencing white space. Clarify whether Etomidate is intended for monotherapy, combination, maintenance, rescue or an earlier treatment line.

White space should be framed as an unanswered development question, not merely an unoccupied mechanism label. A credible program closes a measurable clinical uncertainty with a design that can be executed and interpreted.

Strategic implications and next readouts

For sponsors, the endpoint hierarchy, safety window, enrollment pace and protocol amendment history should all support the same target product profile. Advancement criteria should be set before the readout and tied to clinical effect, uncertainty, tolerability and operational feasibility.

For business-development teams, differentiation may come from a sharper population, stronger comparator, more durable benefit, simpler delivery or clearer sequencing role. For investors, the central risk is evidence quality relative to time and capital, not the phase label in isolation.

Track recruitment status, enrollment changes, primary-completion timing, endpoint revisions, new result records, sponsor ownership and collaborator changes. Re-run the PatSnap MCP workflow when a surrogate becomes a clinical outcome, a single-country study expands, the comparator changes or a new result materially shifts the competitive benchmark.

Source trail and bottom line

Anchor trial: ISRCTN10813814
Protocol source: https://www.isrctn.com/ISRCTN10813814
MCP sources: Clinical Trials MCP (clinical_trial_fetch and clinical_trial_result_fetch); Drug & Asset MCP (drug_fetch); Company & Deal Intelligence MCP (organization_fetch).
Data snapshot: 18 September 2026.

Etomidate in Ovarian Cancer is best understood through the interaction of protocol design, surrounding readouts, asset context and sponsor execution. The current record makes Primary endpoint not reported and 2023-09-30 the leading decision points.

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