Magnesium Carbonate in Surgical Wound Infection: NCT07803601 Clinical Landscape Report 2026

16 September 2026
9 min read

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This Clinical Landscape Report was built with PatSnap Life Sciences MCP workflows. Clinical Trials MCP supplies protocol and result records, Drug & Asset MCP adds asset context, and Company & Deal Intelligence MCP resolves sponsor background. Use the same structured MCP building blocks in your research workflow.

Data snapshot: 16 September 2026. This strategic research report is not medical, regulatory or investment advice. Trial status and dates can change.

Not Applicable

Clinical phase

Recruiting

Recruitment status

52

Planned enrollment

2027-03-01

Primary-completion proxy

Executive view

NCT07803601 evaluates Magnesium Carbonate in Surgical Wound Infection. The disclosed sponsor is Ain Shams University, the design is Interventional, and the geographic footprint is Egypt. The first listed primary endpoint is postoperative white blood cell count (WBC), assessed over inflammatory markers will be measured at 2 time points: 12 and 36 hours after surgery..

The key landscape question is whether this protocol can generate a clinically interpretable signal relative to nearby programs. Phase alone is not a measure of evidence quality. Endpoint relevance, comparator choice, masking, enrollment feasibility, patient selection, country coverage and follow-up must be considered together.

PatSnap MCP Servers make this assessment reproducible by keeping protocol facts, result evidence, asset attributes and sponsor identity in separate structured calls.

How the MCP evidence stack was assembled

Clinical Trials MCP clinical_trial_fetch retrieved the design, outcomes, phase, status, enrollment, sponsor, countries and timing for NCT07803601 and selected peers. clinical_trial_result_fetch supplied detailed result records from the wider Surgical Wound Infection landscape. Drug & Asset MCP drug_fetch was queried for Magnesium Carbonate, while Company & Deal Intelligence MCP organization_fetch was queried for Ain Shams University.

This separation reduces a common diligence error: treating a registry label, a company description or a result excerpt as if each represented the complete evidence package. Explore the source workflow at the PatSnap MCP marketplace.

Trial landscape table

TrialAsset / interventionPhase / statusSponsorGeographyPrimary endpointReadout proxy
NCT07803601Magnesium CarbonateNot Applicable / RecruitingAin Shams UniversityEgyptpostoperative white blood cell count (WBC)
inflammatory markers will be measured at 2 time points: 12 and 36 hou…
2027-03-01
NCT07807800DES-1357Phase 1/2 / Not yet recruitingD.E. Shaw Research LLCGeography not reportedPart 1: Number of Participants With Dose-Limiting Toxicities (DLTs)
Part 1: Cycle 1 (Cycle length=21 days)
2028-07-02
NCT07808151PembrolizumabPhase 2 / Not yet recruitingSolstice Oncology, Inc.Netherlands, Belgium, United States, United Kingdom, Italy, SpainMajor Pathologic Response (MPR) rate by Blinded Independent Pathologic Review (BIPR)
Assessed from surgical resection specimen (surgery occurs Day 42-Day…
2029-09-30
NCT07808177177Lu-FAP-VG11Early Phase 1 / RecruitingShandong First Medical University Affiliated Tumor Hospital (Shandong Cancer Research Institute Shandong Tumor Hospital)ChinaDose-Limiting Toxicities (DLT)
Through study completion, assessed up to 2 years.
2027-05-06
NCT07805369DEM301Phase 1 / Not yet recruitingDEM BioPharma, Inc.Geography not reportedIncidence of Dose-Limiting Toxicities (DLTs)
21 Days
2028-09-01

The table aligns endpoints, sponsors, phases, geographies and readout proxies. It is descriptive, not a head-to-head efficacy comparison. Differences in population, baseline risk, intervention schedule and follow-up can dominate apparent cross-trial differences.

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Protocol design and endpoint interpretation

NCT07803601 is a Not Applicable, recruiting study with 52 planned participants. Allocation is Randomized, masking is Quadruple, and the intervention model is Parallel Assignment.

The primary endpoint is “postoperative white blood cell count (WBC)” over “inflammatory markers will be measured at 2 time points: 12 and 36 hours after surgery..” The retrieved endpoint description is: Assess effect of intravenous magnesium sulfate on postoperative inflammation by serum inflammatory marker as WBCS..

Interpretation should test whether the endpoint captures a clinically meaningful change, whether its time horizon matches the proposed biology, and whether treatment discontinuation or missing data can bias the estimate. The planned enrollment of 52 should be assessed against expected effect size, event frequency, multiplicity, subgroup plans and attrition.

No named control drug was returned in the protocol field set. A placebo comparator can strengthen internal efficacy assessment, while an active comparator may better test clinical differentiation. Single-arm and open-label programs require greater weight on objective outcomes, independent assessment and external benchmarks.

Indexed readouts in the surrounding landscape

5 recent result records were selected as contextual evidence for Surgical Wound Infection. These records do not establish direct evidence for NCT07803601 unless the registration number matches.

Randomized phase-II trial of surufatinib plus FOLFOX/FOLFIRI versus FOLFOXIRI as second-line therapy for metastatic colorectal cancer

Phase 2; n=57; ORR = 39.3 % ( 21.5 - 59.4); ORR = 35.7 % ( 18.6 - 55.9) Source: https://pubmed-ncbi-nlm-nih-gov.libproxy1.nus.edu.sg/42421558/

Phase II Study of Regorafenib in Good Performance Status Patients With Newly Diagnosed Metastatic Colorectal Adenocarcinoma

Phase 2; n=11; No numerical result field reported Source: https://clinicaltrials.gov/ct2/show/results/NCT02023333

Aspirin for cancer prevention in individuals with Lynch syndrome: first results from the CaPP3 multicentre, randomised, double-blind, non-inferiority trial

Phase 3; n=1879; Lynch syndrome cancers = 75.0 Participant ; Lynch syndrome cancers = 57.0 Participant Source: https://pubmed-ncbi-nlm-nih-gov.libproxy1.nus.edu.sg/42425127/

Result fields should be reconciled with the source record before quantitative comparison. Population definitions, analysis sets, dose cohorts, estimands, confidence intervals, rescue therapy and follow-up can materially change the meaning of a numerical endpoint. Clinical Trials MCP supports repeatable refreshes as result records change.

Asset and sponsor context

Magnesium Carbonate is indexed as Small molecule drug with target not reported biology and a global stage of Approved. The asset profile lists Yamazen Co. Ltd. as an originator or developer.

Ain Shams University is indexed in Egypt with the website http://www.asu.edu.eg. Ain Shams University provides study in the field of astronomy, engineering and medicine. The record lists 18 development-stage drug assets.

For execution diligence, monitor sponsor ownership, collaborator additions, site expansion, protocol amendments and enrollment revisions. A change in ownership or geography can alter operational confidence as well as the commercial meaning of a future readout.

Development white space

  1. Endpoint white space. Determine whether a more patient-relevant outcome, longer durability window or blinded central assessment would resolve uncertainty left by the current endpoint.
  2. Population white space. Test biomarker-defined, treatment-line or risk-stratified subgroups where effect size and unmet need could be clearer.
  3. Comparator white space. Identify whether the study can support differentiation against the current standard of care rather than only activity against baseline or placebo.
  4. Geographic white space. Assess whether the disclosed footprint supports recruitment, regulatory transferability and commercial generalizability.
  5. Sequencing white space. Clarify whether Magnesium Carbonate is intended for monotherapy, combination, maintenance, rescue or an earlier treatment line.

White space should be framed as an unanswered development question, not merely an unoccupied mechanism label. A credible program closes a measurable clinical uncertainty with a design that can be executed and interpreted.

Strategic implications and next readouts

For sponsors, the endpoint hierarchy, safety window, enrollment pace and protocol amendment history should all support the same target product profile. Advancement criteria should be set before the readout and tied to clinical effect, uncertainty, tolerability and operational feasibility.

For business-development teams, differentiation may come from a sharper population, stronger comparator, more durable benefit, simpler delivery or clearer sequencing role. For investors, the central risk is evidence quality relative to time and capital, not the phase label in isolation.

Track recruitment status, enrollment changes, primary-completion timing, endpoint revisions, new result records, sponsor ownership and collaborator changes. Re-run the PatSnap MCP workflow when a surrogate becomes a clinical outcome, a single-country study expands, the comparator changes or a new result materially shifts the competitive benchmark.

Source trail and bottom line

Anchor trial: NCT07803601
Protocol source: https://clinicaltrials.gov/study/NCT07803601
MCP sources: Clinical Trials MCP (clinical_trial_fetch and clinical_trial_result_fetch); Drug & Asset MCP (drug_fetch); Company & Deal Intelligence MCP (organization_fetch).
Data snapshot: 16 September 2026.

Magnesium Carbonate in Surgical Wound Infection is best understood through the interaction of protocol design, surrounding readouts, asset context and sponsor execution. The current record makes postoperative white blood cell count (WBC) and 2027-03-01 the leading decision points.

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