Calcium Metabolism Disorders

BOSTON, April 05, 2024 (GLOBE NEWSWIRE) -- Inozyme Pharma, Inc. (Nasdaq: INZY) (“Company” or “Inozyme”), a clinical-stage rare disease biopharmaceutical company developing novel therapeutics for the treatment of pathologic mineralization and intimal proliferation, today announced that it granted stock options to three new employees to purchase shares of the Company’s common stock, pursuant to the Company’s 2023 Inducement Stock Incentive Plan, as inducement material to the new employees entering into employment with the Company in accordance with Nasdaq Listing Rule 5635(c)(4). The Company’s compensation committee granted nonstatutory stock options to purchase up to an aggregate of 80,000 shares of the Company’s common stock to the new employees on April 2, 2024, at an exercise price of $6.93 per share, the closing price per share of the Company’s common stock as reported by Nasdaq on April 2, 2024. The options have a 10-year term and vest over four years, with 25% of the original number of shares vesting on the first anniversary of the employee’s start date and 2.0833% of the shares underlying the option vesting monthly thereafter, subject to such employee’s continued service to the Company through the applicable vesting dates. About Inozyme Pharma Inozyme Pharma, Inc. is a clinical-stage rare disease biopharmaceutical company developing novel therapeutics for the treatment of diseases impacting the vasculature, soft tissue, and skeleton. Inozyme is developing INZ-701, an enzyme replacement therapy, to address pathologic mineralization and intimal proliferation which can drive morbidity and mortality in these severe diseases. INZ-701 is currently in clinical trials for the treatment of ENPP1 Deficiency, ABCC6 Deficiency, and calciphylaxis. For more information, please visit www.inozyme.com or follow Inozyme on LinkedIn, X (formerly Twitter), and Facebook. ContactsInvestors:Inozyme PharmaStefan Riley, Senior Director of IR and Corporate Communications (857) 330-8871stefan.riley@inozyme.com Media: SmithSolve Matt Pera (973) 886-9150matt.pera@smithsolve.com

At the 73rd Annual Conference of the ACC (American College of Cardiology) April 6–8, 2024, Atlanta (GA) LEVALLOIS-PERRET, France--(BUSINESS WIRE)-- Cardiawave SA, a French medtech company that has developed an innovative Non-Invasive focused Ultrasound Therapy (NIUT) device for the treatment of severe symptomatic calcific aortic stenosis, will present the 30-day follow-up results for 60 patients enrolled in its European pivotal study to the 73rd annual conference of the American College of Cardiology in Atlanta, Georgia. This is a leading event in the cardiovascular medicine calendar, which brings together specialists from around the world to discuss the latest advances, research results and clinical innovations in the field of cardiology. Prof. Eric Van Belle, cardiologist at Lille University Hospital, one of the principal investigators for the European pivotal study, commented: “I’m very proud to present the excellent results obtained using Cardiawave’s NIUT device to treat patients with severe symptomatic aortic valve stenosis, leading to a significant improvement in their condition and a better quality of life. This ACC.24 presentation represents a major contribution to the advance of science and will open up innovative therapeutic strategies for cardiology patients.” A summary of the poster session will be published on the Journal of the American College of Cardiology’s website. Presentation title: QUALITY OF LIFE ASSESSMENT AT 30-DAYS FOLLOW-UP OF THE VALVOSOFT® PIVOTAL STUDY ON SEVERE AORTIC VALVE STENOSE PATIENTS" (control number 16930) Time and date: April 8, 2024 - 9:32 a.m.–9:42 a.m. EDT The results of the Cardiawave First-in-Human “Valvosoft® FIM Study” were published in The Lancet in November 2023: (23)01518-0/fulltext About Cardiawave : © Cardiawave, 2024

BOSTON, April 02, 2024 (GLOBE NEWSWIRE) -- Inozyme Pharma, Inc. (Nasdaq: INZY) (“the Company” or “Inozyme”), a clinical-stage rare disease biopharmaceutical company developing novel therapeutics for the treatment of pathologic mineralization and intimal proliferation, today announced that Doug Treco, Ph.D., the company’s chief executive officer and chairman of the board, will participate in a fireside chat at the 23rd Annual Needham Virtual Healthcare Conference on Tuesday, April 9, 2024 from 10:15-10:55 a.m. ET. A live webcast of the fireside chat can be accessed from the Investor Relations section of Inozyme’s website under events, where a replay of the event will also be available for a limited time. About Inozyme Pharma Inozyme Pharma, Inc. is a clinical-stage rare disease biopharmaceutical company developing novel therapeutics for the treatment of diseases impacting the vasculature, soft tissue, and skeleton. Inozyme is developing INZ-701, an enzyme replacement therapy, to address pathologic mineralization and intimal proliferation, which can drive morbidity and mortality in these severe diseases. INZ-701 is currently in clinical development for the treatment of ENPP1 Deficiency, ABCC6 Deficiency and calciphylaxis. For more information, please visit or follow Inozyme on LinkedIn, X (formerly Twitter), and Facebook. Contacts Investors: Inozyme Pharma Stefan Riley, Senior Director of IR and Corporate Communications (857) 330-8871 stefan.riley@inozyme.com Media: SmithSolve Matt Pera (973) 886-9150 matt.pera@smithsolve.com