Bronchogenic Carcinoma

TOKYO & MUNICH--( BUSINESS WIRE )--The European Medicines Agency (EMA) has validated two marketing authorization applications (MAAs) for Daiichi Sankyo (TSE: 4568) and AstraZeneca’s (LSE/STO/Nasdaq: AZN) datopotamab deruxtecan (Dato-DXd) in two types of cancer. One MAA is for the treatment of adult patients with locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) who require systemic therapy following prior treatment. The other MAA is for the treatment of adult patients with unresectable or metastatic hormone receptor (HR) positive, HER2 negative (IHC 0, IHC 1+ or IHC 2+/ISH-) breast cancer who have progressed on and are not suitable for endocrine therapy and received at least one additional systemic therapy. Datopotamab deruxtecan is a specifically engineered TROP2 directed DXd antibody drug conjugate (ADC) discovered by Daiichi Sankyo and being jointly developed by Daiichi Sankyo and AstraZeneca. The validations confirm the completion of the applications and commence the scientific review process by the EMA’s Committee for Medicinal Products for Human Use. The applications are based on data from the pivotal TROPION-Lung01 and TROPION-Breast01 phase 3 trials presented during two Presidential Symposia at the European Society for Medical Oncology (#ESMO23) 2023 Congress. “ The EMA validation is an important first step toward bringing this TROP2 directed antibody drug conjugate to eligible patients in Europe with nonsquamous lung cancer and HR positive, HER2 negative breast cancer,” said Ken Takeshita, MD, Global Head, R&D, Daiichi Sankyo. “ This news builds on our recent regulatory progress in the U.S., where our lung cancer application has been accepted and our breast cancer application is underway, underscoring our commitment to changing the standard of care by developing new medicines to help as many patients worldwide as possible.” “ Our ambition is for datopotamab deruxtecan to improve upon and replace conventional chemotherapy in the treatment of multiple cancer types,” said Susan Galbraith, MBBChir, PhD, Executive Vice President, Oncology R&D, AstraZeneca. “ Today’s dual validation of our applications in lung and breast cancers brings this potential medicine a meaningful step closer to redefining treatment expectations for patients with two of the most common cancers in Europe.” Additional regulatory submissions for datopotamab deruxtecan in lung cancer and breast cancer are underway in the U.S. and globally. About TROPION-Lung01 TROPION-Lung01 is a global, randomized, multicenter, open-label phase 3 trial evaluating the efficacy and safety of datopotamab deruxtecan versus docetaxel in patients with locally advanced or metastatic NSCLC with and without actionable genomic alterations who require systemic therapy following prior treatment. Patients with actionable genomic alterations were previously treated with platinum-based chemotherapy and an approved targeted therapy. Patients without known actionable genomic alterations were previously treated, either in combination or sequentially, with platinum-based chemotherapy and a PD-1 or PD-L1 inhibitor. The dual primary endpoints of TROPION-Lung01 are progression-free survival (PFS) as assessed by blinded independent central review (BICR) and overall survival (OS). Key secondary endpoints include investigator-assessed PFS, objective response rate (ORR), duration of response (DoR), time to response, disease control rate (DCR) as assessed by both BICR and investigator, and safety. TROPION-Lung01 enrolled approximately 600 patients in Asia, Europe, North America and South America. For more information visit ClinicalTrials.gov . About TROPION-Breast01 TROPION-Breast01 is a global, randomized, multicenter, open-label phase 3 trial evaluating the efficacy and safety of datopotamab deruxtecan versus investigator’s choice of single-agent chemotherapy (eribulin, capecitabine, vinorelbine or gemcitabine) in patients with unresectable or metastatic HR positive, HER2 negative (IHC 0, IHC 1+ or IHC 2+/ISH-) breast cancer who have progressed on and are not suitable for endocrine therapy per investigator assessment and have received at least one additional systemic therapy for unresectable or metastatic disease. The dual primary endpoints of TROPION-Breast01 are PFS as assessed by BICR and OS. Key secondary endpoints include ORR, DoR, investigator-assessed PFS, DCR, time to first subsequent therapy and safety. TROPION-Breast01 enrolled more than 700 patients in Africa, Asia, Europe, North America and South America. For more information visit ClinicalTrials.gov . About Advanced Non-Small Cell Lung Cancer Nearly 500,000 lung cancer cases were diagnosed in Europe in 2022. 1 NSCLC is the most common type of lung cancer, accounting for about 80% of cases. 1 Approximately 70% and 30% of NSCLC tumors are of nonsquamous or squamous histology, respectively. 2 While immunotherapy and targeted therapies have improved outcomes in the first-line setting, most patients eventually experience disease progression and receive chemotherapy. 3,4,5 For decades, chemotherapy has been the last treatment available for patients with advanced NSCLC, despite limited effectiveness and known side effects. 3,4,5 About Hormone Receptor Positive, HER2 Negative Breast Cancer More than 500,000 breast cancer cases were diagnosed in Europe in 2022. 6 HR positive, HER2 negative breast cancer is the most common subtype, accounting for more than 65% of diagnosed cases. 7 Breast cancer is considered HR positive, HER2 negative when tumors test positive for estrogen and/or progesterone hormone receptors and negative for HER2 (measured as HER2 score of IHC 0, IHC 1+ or IHC 2+/ISH-). 7,8 Standard initial treatment for this subtype of breast cancer is endocrine therapy but most patients with advanced disease will develop resistance, underscoring the need for additional options. 9,10 About TROP2 TROP2 is a protein broadly expressed in several solid tumors, including the majority of NSCLC and HR positive, HER2 negative breast cancer cases. 11,12 High TROP2 expression is associated with increased tumor progression and poor survival. 12,13 There is currently no TROP2 directed ADC approved for the treatment of lung cancer. 14,15 About Datopotamab Deruxtecan (Dato-DXd) Datopotamab deruxtecan (Dato-DXd) is an investigational TROP2 directed ADC. Designed using Daiichi Sankyo’s proprietary DXd ADC Technology, datopotamab deruxtecan is one of six DXd ADCs in the oncology pipeline of Daiichi Sankyo, and one of the most advanced programs in AstraZeneca’s ADC scientific platform. Datopotamab deruxtecan is comprised of a humanized anti-TROP2 IgG1 monoclonal antibody, developed in collaboration with Sapporo Medical University, attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptide-based cleavable linkers. A comprehensive development program called TROPION is underway globally with more than 14 trials evaluating the efficacy and safety of datopotamab deruxtecan across multiple cancers, including NSCLC, triple negative breast cancer and HR positive, HER2 negative breast cancer. Beyond the TROPION program, datopotamab deruxtecan also is being evaluated in novel combinations in several ongoing trials. About the Daiichi Sankyo and AstraZeneca Collaboration Daiichi Sankyo and AstraZeneca entered into a global collaboration to jointly develop and commercialize ENHERTU in March 2019 and datopotamab deruxtecan in July 2020 , except in Japan where Daiichi Sankyo maintains exclusive rights for each ADC. Daiichi Sankyo is responsible for the manufacturing and supply of ENHERTU and datopotamab deruxtecan. About the DXd ADC Portfolio of Daiichi Sankyo The DXd ADC portfolio of Daiichi Sankyo currently consists of six ADCs in clinical development across multiple types of cancer. ENHERTU, a HER2 directed ADC, and datopotamab deruxtecan, a TROP2 directed ADC, are being jointly developed and commercialized globally with AstraZeneca. Patritumab deruxtecan (HER3-DXd), a HER3 directed ADC, ifinatamab deruxtecan (I-DXd), a B7-H3 directed ADC, and raludotatug deruxtecan (R-DXd), a CDH6 directed ADC, are being jointly developed and commercialized globally with Merck & Co., Inc., Rahway, N.J. USA. DS-3939, a TA-MUC1 directed ADC, is being developed by Daiichi Sankyo. Designed using Daiichi Sankyo’s proprietary DXd ADC Technology to target and deliver a cytotoxic payload inside cancer cells that express a specific cell surface antigen, each ADC consists of a monoclonal antibody attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptide-based cleavable linkers. Datopotamab deruxtecan, ifinatamab deruxtecan, patritumab deruxtecan, raludotatug deruxtecan and DS-3939 are investigational medicines that have not been approved for any indication in any country. Safety and efficacy have not been established. About Daiichi Sankyo Daiichi Sankyo is an innovative global healthcare company contributing to the sustainable development of society that discovers, develops and delivers new standards of care to enrich the quality of life around the world. With more than 120 years of experience, Daiichi Sankyo leverages its world-class science and technology to create new modalities and innovative medicines for people with cancer, cardiovascular and other diseases with high unmet medical need. For more information, please visit www.daiichisankyo.com . ________________________________ References: 1 Cancer.net. Lung Cancer – Non-Small Cell: Statistics . Accessed March 2024. 2 National Cancer Institute. SEER Cancer Statistics Factsheets: Lung and Bronchus Cancer, 2015 . Accessed March 2024. 3 Chen R, et al. J Hemal Oncol . 2020;13(1):58. 4 Majeed U, et al. J Hematol Oncol . 2021;14(1):108 5 Pircher A, et al. Anticancer Research . 2020;70(5):287-294. 6 Globocan 2022. Europe . Accessed February 2024. 7 National Cancer Institute. SEER cancer stat facts: female breast cancer subtypes . Accessed March 2024. 8 Iqbal N, et al. Mol Biol Int . 2014;852748. 9 Lin M, et al. J Cancer . 2020; 10.7150/jca.48944. 10 Lloyd M R, et al. Clin Cancer Res. 2022; 28(5):821-30. 11 Goldenberg D, et al. Oncotarget . 2018;9(48): 28989-29006. 12 Mito R, et al. Pathol Int . 2020;70(5):287-294. 13 Vidula N, et al. Breast Cancer Res Treat . 2022 Aug;194(3):569-575. 14 Rodríguez-Abreau D et al. Ann Onc . 2021 Jul;32(7): 881-895. 15 American Cancer Society. Targeted Drug Therapy for Non-Small Cell Lung Cancer . Accessed March 2024.

Application based on results from the TROPION-Lung01 phase 3 trial If approved, Daiichi Sankyo and AstraZeneca’s datopotamab deruxtecan may be the first TROP2 directed antibody drug conjugate for patients with lung cancer TOKYO & BASKING RIDGE, N.J.--(BUSINESS WIRE)-- Daiichi Sankyo (TSE: 4568) and AstraZeneca’s (LSE/STO/Nasdaq: AZN) Biologics License Application (BLA) for datopotamab deruxtecan (Dato-DXd) has been accepted in the U.S. for the treatment of adult patients with locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) who have received prior systemic therapy. Datopotamab deruxtecan is a specifically engineered TROP2 directed DXd antibody drug conjugate (ADC) being jointly developed by Daiichi Sankyo and AstraZeneca. The Prescription Drug User Fee Act (PDUFA) date, the U.S. Food and Drug Administration (FDA) action date for its regulatory decision, is December 20, 2024. The BLA is based on results from the pivotal TROPION-Lung01 phase 3 trial presented at a Presidential Symposium at the European Society for Medical Oncology (#ESMO23) 2023 Congress. In the trial, datopotamab deruxtecan demonstrated a statistically significant improvement for the dual primary endpoint of progression-free survival (PFS) compared to docetaxel, the current standard of care, in patients with locally advanced or metastatic NSCLC treated with at least one prior line of therapy. For the dual primary endpoint of overall survival (OS), interim results numerically favored datopotamab deruxtecan over docetaxel in the overall population, however, results did not reach statistical significance at the time of data cut-off. In patients with nonsquamous NSCLC, datopotamab deruxtecan showed a clinically meaningful PFS benefit and a numerically favorable OS trend. The trial is ongoing and OS will be assessed at final analysis. The safety pro datopotamab deruxtecan was consistent with that observed in other ongoing trials with no new safety concerns identified. “Today’s news is an important step forward in our goal of creating new standards of care that have the potential to transform the treatment of patients with non-small cell lung cancer,” said Ken Takeshita, MD, Global Head, R&D, Daiichi Sankyo. “We are encouraged by the FDA's acceptance of the BLA as we endeavor to make datopotamab deruxtecan the first TROP2 directed antibody drug conjugate approved to treat patients with nonsquamous non-small cell lung cancer after disease progression on prior systemic therapy. We look forward to working closely with the FDA to bring datopotamab deruxtecan to patients.” “Datopotamab deruxtecan has the potential to offer patients with previously treated advanced nonsquamous non-small cell lung cancer an effective and tolerable alternative to conventional chemotherapy,” said Susan Galbraith, MBBChir, PhD, Executive Vice President, Oncology R&D, AstraZeneca. “With regulatory discussions ongoing around the world and a parallel submission underway in the U.S. in breast cancer, this is only the beginning of our efforts to make this novel treatment available to patients as quickly as possible.” A parallel BLA for datopotamab deruxtecan based on results from the pivotal TROPION-Breast01 phase 3 trial is pending acceptance in the U.S. for the treatment of adult patients with metastatic hormone receptor (HR) positive, HER2 negative (IHC 0, IHC 1+ or IHC 2+/ISH-) breast cancer. Additional regulatory submissions for datopotamab deruxtecan in lung and breast cancer are underway globally. About TROPION-Lung01 TROPION-Lung01 is an ongoing global, randomized, multicenter, open-label phase 3 trial evaluating the efficacy and safety of datopotamab deruxtecan versus docetaxel in patients with locally advanced or metastatic NSCLC with and without actionable genomic alterations previously treated with at least one prior line of therapy. Patients with actionable genomic alterations were previously treated with platinum-based chemotherapy and an approved targeted therapy. Patients without known actionable genomic alterations were previously treated, concurrently or sequentially, with platinum-based chemotherapy and a PD-1 or PD-L1 inhibitor. The dual primary endpoints of TROPION-Lung01 are PFS as assessed by blinded independent central review (BICR) and OS. Key secondary endpoints include investigator-assessed PFS, objective response rate, duration of response, time to response, disease control rate as assessed by both BICR and investigator, and safety. TROPION-Lung01 enrolled approximately 600 patients in Asia, Europe, North America and South America. For more information visit ClinicalTrials.gov. About Advanced Non-Small Cell Lung Cancer Nearly 250,000 lung cancer cases were diagnosed in the U.S. in 2023.1 NSCLC is the most common type of lung cancer, accounting for about 80% of cases.1 Approximately 70% and 30% of NSCLC tumors are of nonsquamous or squamous histology, respectively.2 While immunotherapy and targeted therapies have improved outcomes in the first-line setting, most patients eventually experience disease progression and receive chemotherapy.3,4,5 For decades, chemotherapy has been the last treatment available for patients with advanced NSCLC, despite limited effectiveness and known side effects.3,4,5 TROP2 is a protein broadly expressed in the majority of NSCLC tumors.6 There is currently no TROP2 directed ADC approved for the treatment of lung cancer.7,8 About Datopotamab Deruxtecan (Dato-DXd) Datopotamab deruxtecan (Dato-DXd) is an investigational TROP2 directed ADC. Designed using Daiichi Sankyo’s proprietary DXd ADC Technology, datopotamab deruxtecan is one of six DXd ADCs in the oncology pipeline of Daiichi Sankyo, and one of the most advanced programs in AstraZeneca’s ADC scientific platform. Datopotamab deruxtecan is comprised of a humanized anti-TROP2 IgG1 monoclonal antibody, developed in collaboration with Sapporo Medical University, attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptide-based cleavable linkers. A comprehensive development program called TROPION is underway globally with more than 14 trials evaluating the efficacy and safety of datopotamab deruxtecan across multiple cancers, including NSCLC, triple negative breast cancer and HR positive, HER2 negative breast cancer. Beyond the TROPION program, datopotamab deruxtecan also is being evaluated in novel combinations in several ongoing trials. About the Daiichi Sankyo and AstraZeneca Collaboration Daiichi Sankyo and AstraZeneca entered into a global collaboration to jointly develop and commercialize ENHERTU in March 2019 and datopotamab deruxtecan (Dato-DXd) in July 2020, except in Japan where Daiichi Sankyo maintains exclusive rights for each ADC. Daiichi Sankyo is responsible for the manufacturing and supply of ENHERTU and datopotamab deruxtecan. About the DXd ADC Portfolio of Daiichi Sankyo The DXd ADC portfolio of Daiichi Sankyo currently consists of six ADCs in clinical development across multiple types of cancer. ENHERTU, a HER2 directed ADC, and datopotamab deruxtecan, a TROP2 directed ADC, are being jointly developed and commercialized globally with AstraZeneca. Patritumab deruxtecan (HER3-DXd), a HER3 directed ADC, ifinatamab deruxtecan (I-DXd), a B7-H3 directed ADC, and raludotatug deruxtecan (R-DXd), a CDH6 directed ADC, are being jointly developed and commercialized globally with Merck & Co., Inc., Rahway, N.J. USA. DS-3939, a TA-MUC1 directed ADC, is being developed by Daiichi Sankyo. Designed using Daiichi Sankyo’s proprietary DXd ADC Technology to target and deliver a cytotoxic payload inside cancer cells that express a specific cell surface antigen, each ADC consists of a monoclonal antibody attached to a number of topoisomerase I inhibitor payloads (an exatecan derivative, DXd) via tetrapeptide-based cleavable linkers. Datopotamab deruxtecan, ifinatamab deruxtecan, patritumab deruxtecan, raludotatug deruxtecan and DS-3939 are investigational medicines that have not been approved for any indication in any country. Safety and efficacy have not been established. About Daiichi Sankyo Daiichi Sankyo is an innovative global healthcare company contributing to the sustainable development of society that discovers, develops and delivers new standards of care to enrich the quality of life around the world. With more than 120 years of experience, Daiichi Sankyo leverages its world-class science and technology to create new modalities and innovative medicines for people with cancer, cardiovascular and other diseases with high unmet medical need. For more information, please visit . References: 1 Cancer.net. Lung Cancer – Non-Small Cell: Statistics. Accessed February 2024. 2 National Cancer Institute. SEER Cancer Statistics Factsheets: Lung and Bronchus Cancer, 2015. Accessed February 2024. 3 Chen R, et al. J Hemal Oncol. 2020;13(1):58. 4 Majeed U, et al. J Hematol Oncol. 2021;14(1):108 5 Pircher A, et al. Anticancer Research. 2020;70(5):287-294. 6 Mito R, et al. Pathol Int. 2020;70(5):287-294. 7 Rodríguez-Abreau D et al. Ann Onc. 2021 Jul;32(7): 881-895. 8 American Cancer Society. Targeted Drug Therapy for Non-Small Cell Lung Cancer. Accessed February 2024. View source version on businesswire.com: Contacts Investor Relations Contact: DaiichiSankyoIR@daiichisankyo.co.jp Source: Daiichi Sankyo View this news release online at:

DUBLIN--( BUSINESS WIRE )--The "USA Solid Tumor Therapeutics Market Outlook to 2028" report has been added to ResearchAndMarkets.com's offering. The USA Solid Tumor Therapeutics Market refers to the pharmaceutical & biotechnology sector focused on developing & marketing treatments for various types of solid tumors, which are cancerous growths that forms in the tissues such as the breast, lung, prostate, colon & more. The market consists of wide range of therapies, including chemotherapy, targeted therapies, immunotherapies & emerging approaches like gene & cell therapies. United States holds a significant share in the solid tumor therapeutics market. Solid tumors are a significant healthcare concern in the United States, contributing to a significant portion of cancer cases & mortality. The prevalence of various types of tumors, such as breasts, lungs & colorectal cancers, has driven the demand for therapeutic options. Advancements in our understanding about cancer biology, genomics, & molecular pathways have led to development of targeted therapies that can specifically target the underlying genetic mutations driving tumor growth. These targeted therapies often have fewer side effects. The concept of personalized medicine has gained traction, allowing for tailored treatment approaches based on an individual's genetic makeup. Some leading players within the market include AstraZeneca, Novartis, Pfizer etc. They're known for providing certain therapies for different types of solid tumor. The USA Solid Tumor Therapeutics Market is a mix of consolidated & fragmented players. It is dominated by several large pharmaceutical players like AstraZeneca, Ipsen, Pfizer etc. which sell a wide range of products targeting various types of products targeting various types of solid tumors. On the other hand, the market also features a significant number of smaller biotech companies & startups that focus on developing specialized therapies of solid tumors or novel approaches to treatment. USA Solid Tumor Therapeutics Market Analysis Around 1.9 million new cases were estimated to be diagnosed in United States in 2023, out of which 153,000 cases are colorectal cancer cases, 238,300 cases of lungs & bronchus cancers will be diagnosed. Therefore, the region's high burden of cases is projected to boost the R&D for solid tumor therapeutics As the number of elderly people grew within the United States, there was an increasing demand for cancer diagnosis. In 2022, breast, lungs, prostate & colorectal cancer accounted for the largest cases in the United States The US Food & Drug Administration (FDA), a government regulatory agency under the Health & Human Services, controls the drug approval process & is tasked with reviewing new drugs & devices before companies start selling them. The process involves discovery/concept, preclinical research, clinical research, FDA review & FDA post-market safety monitoring Key Trends by Market Segment: By Type: Breast cancer has been the dominant segment in 2022, owing to the increasing number of breast cancer cases & other internal & external factors like genetics, lifestyle, environmental factors & awareness which are leading to early detection. Breast cancer market is forecasted to grow further, due to high burden of cancer & rising launches of market players By Application: Cancer research center has been the dominant market in 2022. These centers' prominent focus is on cancer care, as they offer diagnostic capabilities, cutting edge treatments, clinical trials & comprehensive support care services By Geography: In 2022, the Northern area of the USA which includes states like New York, Massachusetts & Pennsylvania dominate the solid tumor therapeutics market in the United States because of major medical & research institutions, making it a hub for biotechnology & pharmaceutical companies Competitive Landscape: The USA Solid Tumor Therapeutics market consists of a wide range of companies- from pharmaceutical giants such as Pfizer & Novartis, which have a vast portfolio of oncology drugs that target various kinds of tumors including breast lungs & colorectal cancers. Numerous biotech firms are engaged in developing cutting edge therapies for solid tumors. Companies like Amgen, Gilead Sciences & Celgene have been at the forefront of research & innovation in this field. Targeted therapies which focus on specific genetic mutations or protein expressions have gained prominence. Companies like AstraZeneca, Pfizer & Bayer have started developing targeted therapies that cater to the unique characteristics of different solid tumors. The solid tumor market continues to attract small & emerging biotech companies that are working on novel approaches. These companies often focus on niche indications or unique mechanisms of action, attempting to bring innovation in market. Future Outlook: The market is expected to show increasing and is expected to grow at a CAGR of ~10% from 2022 to 2028 with technological advancements, regulatory policies & healthcare policies leading to advancing growth of the market. The field of oncology is moving towards more personalized treatment approaches, where therapies are tailored to an individual patient's genetic & molecular profile. Immunotherapies like immune checkpoint inhibitors and CAR-T cell therapies, has shown positive results in treating certain types of solid tumors. Ongoing research & development in this area can lead to expansion of immunotherapy applications to a wide range of settings. The discovery & development of new drug classes, such as small molecule inhibitors & antibody drug conjugates, could provide additional treatment options for solid tumor patients. Advances in diagnostic technologies, such as liquid biopsies and advanced imaging techniques, could lead to earlier & more accurate detection, enabling timely interventions. Company Profiles Pfizer Novartis AstraZeneca Eli Lilly & Company Amgen Johnson & Johnson Memorial Sloan Kettering Cancer Center Key Topics Covered: 1. Executive Summary 2. USA Solid Tumor Therapeutics Market Overview 2.1 Taxonomy of the USA Solid Tumor Therapeutics Market 2.2 Industry Value Chain 2.3 Ecosystem 2.4 Government Regulations/Initiatives for the USA Solid Tumor Therapeutics Market 2.5 Growth Drivers of the USA Solid Tumor Therapeutics Market 2.6 Issues and Challenges of the USA Solid Tumor Therapeutics Market 2.7 Impact of COVID-19 on the Market 2.8 SWOT Analysis 3. USA Solid Tumor Therapeutics Market Size, 2017-2022 4. USA Solid Tumor Therapeutics Market Segmentation 4.1 By Product Type, 2017-2022 4.2 By Application, 2017-2022 4.3 By Regional Split (North/East/West/South), 2017-2022 5. Competitive Landscape 5.1 Mergers and Acquisitions, Joint Ventures, Collaborations, and Agreements 5.2 Strategies Adopted by Leading Players 5.3 Company Profiles 6. USA Solid Tumor Therapeutics Future Market Size, 2022-2027 7. USA Solid Tumor Therapeutics Future Market Segmentation 7.1 By Product Type, 2022-2028 7.2 By Application, 2022-2028 7.3 By Regional Split (North/East/West/South), 2022-2028 8. Analyst Recommendations For more information about this report visit https://www.researchandmarkets.com/r/ph6zmn About ResearchAndMarkets.com ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.