Synonyms Chandler Syndrome, Chandler syndrome, Chandler syndrome (disorder) + [31] |
Introduction A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA. |
Target |
Mechanism PD-1 inhibitors |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. China |
First Approval Date24 Dec 2018 |
Target- |
Mechanism Cell replacements |
Active Org. |
Originator Org. |
Inactive Indication- |
Drug Highest PhasePhase 1 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target- |
Mechanism Cell replacements |
Active Org.- |
Originator Org. |
Active Indication- |
Inactive Indication |
Drug Highest PhasePending |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date25 Nov 2022 |
Sponsor / Collaborator |
Start Date08 Nov 2022 |
Sponsor / Collaborator |
Start Date23 Nov 2021 |
Sponsor / Collaborator [+1] |