Synonyms BASAL CELL CARCINOMA, BASAL CELL CARCINOMA OF SKIN, BASAL CELL EPITHELIOMA + [66] |
Introduction A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471) |
Target |
Mechanism HER2 antagonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date17 Apr 2020 |
Target |
Mechanism PD-1 inhibitors |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date28 Sep 2018 |
Target |
Mechanism PI3Kα inhibitors [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date14 Sep 2017 |
Start Date01 Jun 2025 |
Sponsor / Collaborator |
Start Date01 Mar 2025 |
Sponsor / Collaborator Rise Therapeutics LLCStartup |
Start Date01 Jan 2025 |
Sponsor / Collaborator |