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Last update 08 May 2025

Nevus of Ota

Last update 08 May 2025

Basic Info

Synonyms

Congenital melanosis bulbi, Naevus fuscocaeruleus ophthalmomaxillaris, Naevus fuscoceruleus ophthalmomaxillaris

+ [35]

Introduction

A macular lesion on the side of the FACE, involving the CONJUNCTIVA and EYELIDS, as well as the adjacent facial skin, SCLERA; OCULOMOTOR MUSCLES; and PERIOSTEUM. Histological features vary from those of a MONGOLIAN SPOT to those of a BLUE NEVUS.

Clinical Trials associated with Nevus of Ota

JPRN-UMIN000045579

/ SuspendedNot ApplicableIIT

Assessments of perioperative respiratory pattern with non-contact vital sign monitor in children undergoing minor surgery: Exploratory observational study. - Assessments of perioperative respiratory pattern with non-contact vital sign monitor in children undergoing surgery.

Start Date29 Sep 2021

Sponsor / Collaborator-

ChiCTR2100047436

/ RecruitingEarly Phase 1IIT

A prospective, randomized, self-controlled clinical trial of large spot low energy picosecond laser in the treatment of Ota nevus

Start Date01 Jul 2021

Sponsor / Collaborator-

TCTR20210223004

/ Not yet recruitingNot ApplicableIIT

Prevalence and Characteristics of Ocular Manifestation of Patients with the Nevus of Ota: A Laser Flare-Cell Photometric Examination

Start Date01 Mar 2021

Sponsor / Collaborator

Mahidol University

100 Clinical Results associated with Nevus of Ota

100 Translational Medicine associated with Nevus of Ota

0 Patents (Medical) associated with Nevus of Ota

772

Literatures (Medical) associated with Nevus of Ota

01 Apr 2025·Archivos de la Sociedad Española de Oftalmología (English Edition)

Primary orbital melanoma in a patient with nevus of Ota

Article

Author: Piñas Hormeño, H ; Segura Fernández-Nogueras, M V ; Tirado Pascual, M ; Alba Linero, C

Primary orbitary melanoma is a very rare malignancy which grows adjacent to melanocyte-rich areas. This is the case of a 48 years-old woman with oculodermal melanocytosis who develops a primary orbital melanoma. After the first approach with exeresis and adjuvant radiotherapy and a subsequent management with orbital exenteration and adjuvant immunotherapy; the patient has reached a remission period of 12 months so far. With this case the aims are to emphasize the severe complications potentially associated to the oculodermal melanocytosis and to demonstrate the need of treating complex patients through multidisciplinary teams.

17 Feb 2025·Journal of Cosmetic and Laser Therapy

Congenital halo nevus associated with vitiligo aggravated by lasers targeting nevus of Ota: a case report

Article

Author: Jiang, Xian ; Sihan, Yan ; Yu, Pan

An 11-year-old Chinese girl had bluish-gray hyperpigmented patches combined with two dark brown papules on her left face since birth, and she developed a hypopigmented patch within the bluish-gray patches after sun exposure at the age of eight. Her previous medical history suggested that the hypopigmented patch was sensitive to the treatment of tacrolimus ointment cream and 308-nm excimer laser, while the hyperpigmented patches were insensitive to the previous initial laser treatment. Based on the clinical manifestations and a positive result of Wood's lamp examination, she was diagnosed with nevus of Ota, congenital halo nevus, and vitiligo. Only three cases of the co-occurrence of nevus of Ota and vitiligo within one area have been reported to date, while this is the first case to present a concurrence of congenital halo nevus and vitiligo within the area of nevus of Ota in the literature.

31 Jan 2025·Cureus

A Case of Nevus of Ota in Trinidad and Tobago

Article

Author: Seemongal-Dass, Robin R ; Singh, Alyssa P ; Seemongal-Dass, Rajiv V ; Conocchiari, Diego A

Oculodermal melanocytosis, also known as Nevus of Ota, was extensively described in 1939 and is characterized by unilateral, irregular, bluish-black cutaneous pigmentation along the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. This condition is non-hereditary and occurs more commonly in females. To the best of our knowledge, we report the first documented case of Nevus of Ota in Trinidad and Tobago, presenting in a 67-year-old female with characteristic pigmentation and no family history of similar conditions. The diagnosis was confirmed clinically, and the patient was counseled on potential ocular and dermatological complications. This case highlights the importance of recognizing rare dermatological conditions in diverse populations to facilitate timely diagnosis, appropriate management, and effective monitoring for potential complications.

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