Last update 14 Apr 2025

Amlodipine Besylate/Irbesartan/Hydrochlorothiazide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
AT1R x NCC x VDCCs
Action
antagonists, inhibitors, blockers
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication-
Originator Organization
WinMedica
Active Organization
WinMedica
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Czechia (18 Feb 2019),
Hypertension
Regulation-
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Structure/Sequence

Molecular FormulaC7H8ClN3O4S2
InChIKeyJZUFKLXOESDKRF-UHFFFAOYSA-N
CAS Registry58-93-5
View All Structures (3)

Related

1
Clinical Trials associated with Amlodipine Besylate/Irbesartan/Hydrochlorothiazide
NCT00224549
/ CompletedPhase 4IIT
Management of Resistant Hypertension -Pharmacokinetic Assessment of Different Antihypertensive Regimen -Comparison of Two Treatment Strategies: Increase Sodium Depletion or Combined Blockage of Renin-angiotensin System (RAS)
100 Clinical Results associated with Amlodipine Besylate/Irbesartan/Hydrochlorothiazide
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100 Translational Medicine associated with Amlodipine Besylate/Irbesartan/Hydrochlorothiazide
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100 Patents (Medical) associated with Amlodipine Besylate/Irbesartan/Hydrochlorothiazide
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100 Deals associated with Amlodipine Besylate/Irbesartan/Hydrochlorothiazide
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External Link

KEGGWikiATCDrug Bank
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C09DX
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
Czechia
WinMedica
18 Feb 2019
Hypertension
Greece
WinMedica
18 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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