Last update 23 Jan 2025

Dapivirine/Levonorgestrel

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
PR x RT
Mechanism
PR antagonists(Progesterone receptor antagonists), RT inhibitors(Reverse transcriptase inhibitors)
Therapeutic Areas
Other Diseases
Active Indication
Hemorrhage
Inactive Indication-
Originator Organization
International Partnership for MicrobicidesInternational Partnership for Microbicides
Active Organization
INC Research Holdings, Inc.
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC21H28O2
InChIKeyWWYNJERNGUHSAO-XUDSTZEESA-N
CAS Registry797-63-7
View All Structures (2)

Related

2
Clinical Trials associated with Dapivirine/Levonorgestrel
NCT05041699
/ CompletedPhase 1/2
A Randomized, Double-Blind, Phase 1b Study in Healthy HIV-Negative Women to Evaluate the Pharmacokinetics, Safety, and Bleeding Patterns Associated With 90-Day Use of Core-Sheath Vaginal Rings Releasing Dapivirine and Levonorgestrel
NCT03467347
/ CompletedPhase 1
A Randomized, Phase 1, Open-Label Study in Healthy HIV-Negative Women to Evaluate the Pharmacokinetics, Safety and Bleeding Patterns Associated With 90-Day Use of Matrix Vaginal Rings Containing 200 mg Dapivirine and 320 mg Levonorgestrel
100 Clinical Results associated with Dapivirine/Levonorgestrel
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100 Translational Medicine associated with Dapivirine/Levonorgestrel
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100 Patents (Medical) associated with Dapivirine/Levonorgestrel
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100 Deals associated with Dapivirine/Levonorgestrel
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemorrhagePhase 2
US
INC Research Holdings, Inc.
20 Jun 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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