Delving into the Latest Updates on Natural killer cell therapy(Shanghai iCELL Biotechnology) with Synapse

Overview

Basic Info

Drug Type

Immune cell therapy

Synonyms-

Target-

Mechanism

Cell replacements

Therapeutic Areas

Neoplasms

Active Indication

Residual Neoplasm

Inactive Indication

Paraparesis, Tropical Spastic

Originator Organization

Shanghai Saiao Biotechnology Co. Ltd.

Active Organization

Shanghai Saiao Biotechnology Co. Ltd.

Inactive Organization-

Drug Highest PhasePreclinical

First Approval Date-

Regulation-

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HTLV-1 Associated Myelopathy is a chronic disease of the spinal cord, caused by a virus called human T lymphotropic virus type 1（HTLV-1）. Natural Killer cells provide rapid responses to viral-infected cells, acting at around 3 days after infection, and respond to tumor formation. In this trial, the investigators aim to study the therapeutic safety and the effect on HTLV-1 virus. This in turn will improve the knowledge and understanding of the disease and should lead to better therapy.

Start Date01 Jul 2016

Sponsor / Collaborator-

NCT02185781 / CompletedPhase 1IIT

Phase I Protocol of Adoptive Immunotherapy With Enriched and Expanded Autologous Natural Killer (NK) Cells for Patients With Ph+ Acute Lymphoblastic Leukemia (ALL) in Complete Hematologic Remission (CHR) But With Persistent/Recurrent Minimal Residual Disease (MRD) ≥60 Years or Not Eligible for Other Post-CHR Treatment Modalities

The present study aims at studying how safe and tolerable a new therapy for patients with Acute Lymphoblastic Leukemia (ALL) is.
This new therapy consists of an immunotherapy, that is an approach focusing on the immune system, and it targets ALL patients in complete remission but who may still have the disease at a cellular level (this is called 'minimal residual disease').
For any further information, please, discuss with your treating physician.

Start Date28 Jan 2015

Sponsor / Collaborator

Gruppo Italiano Malattie EMatologiche dell'Adulto

100 Clinical Results associated with Natural killer cell therapy(Shanghai iCELL Biotechnology)

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100 Translational Medicine associated with Natural killer cell therapy(Shanghai iCELL Biotechnology)

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100 Patents (Medical) associated with Natural killer cell therapy(Shanghai iCELL Biotechnology)

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100 Deals associated with Natural killer cell therapy(Shanghai iCELL Biotechnology)

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