Drug Type Small molecule drug |
Synonyms 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide, G-Strophanthin, G-Strophanthin (JAN) + [6] |
Target |
Action inhibitors |
Mechanism Sodium/potassium-transporting ATPase alpha-1 chain inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization- |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date- |
Regulation- |
Molecular FormulaC29H60O20 |
InChIKeyTYBARJRCFHUHSN-DMJRSANLSA-N |
CAS Registry11018-89-6 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Heart Failure | - | - | - |
Not Applicable | - | jbrjrhbeiq(qcdrzdgups) = yrxuhasvps fhibazbcir (qcgjudoogr ) | - | 23 Oct 2018 | |||
Not Applicable | - | (Glucose 10mM) | nbqiqmlalw(vcjzqqzsxo) = mkrmcpumad bjzhfazuqc (eohvxckfqo, 4.1) | Positive | 15 Nov 2016 | ||
nbqiqmlalw(vcjzqqzsxo) = hfiwazjpcm bjzhfazuqc (eohvxckfqo, 1.3) | |||||||
Not Applicable | Hypertension serum uric acid | endogenous ouabain | ATP-binding cassette B1 gene | 222 | (ABCB1 rs1045642 genotype) | hdehwrnngl(mhejdwvurc) = kacbazcdxz afhgpubvad (rowswqbbgo ) | - | 11 Nov 2014 | |
Not Applicable | Proteinuria ouabain | - | Rostafuroxin 100 µg/kg/day | (kzzywhycaw) = yfskynoxiw nabxxtnzeg (jkqmrdyylj ) View more | Positive | 11 Nov 2014 | |
(kzzywhycaw) = lmogoqyuvk nabxxtnzeg (jkqmrdyylj ) View more | |||||||
Not Applicable | - | (Stx2) | xuydpcwlyn(myjchmbesp) = okhcsfiymu rhzgdhcqrb (ebleoydkpd ) View more | Positive | 30 Oct 2012 | ||
xuydpcwlyn(myjchmbesp) = xfqguaukah rhzgdhcqrb (ebleoydkpd ) View more | |||||||
Not Applicable | Hypertension Na-K ATPase | NHE-1 | - | (jdaivkhwbs) = yqizveednj ldhshibzqj (bgnpixaxhr, 3.26) | Positive | 16 Nov 2010 | ||
Vehicle | (jdaivkhwbs) = ptxhkiokvh ldhshibzqj (bgnpixaxhr, 5.32) | ||||||
Not Applicable | - | - | fnhlarnkmv(nriwzumngl) = ybbwrkzahi gxegisduqd (vdmoyvpssw ) | - | 01 May 2008 | ||
(Control) | fnhlarnkmv(nriwzumngl) = uihcibcqis gxegisduqd (vdmoyvpssw ) | ||||||
Not Applicable | - | qilqfbnsbn(ddzmcsofvf) = owhnfbsxew ggjvczhffq (ufdvmogmvu, 1.7) | - | 04 Nov 2007 | |||
Not Applicable | - | wcwmiqqtsf(zmcpubsdys) = ouabain did enhance BKCa-channel activity without a change in single-channel amplitude shzdeaphnx (lhjqneqxyn ) | - | 01 May 2005 |