Last update 18 Jul 2025

GTB-4550

Overview

Basic Info

Drug Type
Trispecific killer cell engager (TriKE)
Synonyms
GTB-4550 TriKE, GTB 4550, GTB-4550
Target
CD16a x IL15R x PDL1
Action
modulators, agonists, inhibitors
Mechanism
CD16a modulators(Low affinity immunoglobulin gamma Fc region receptor III-A modulators), IL15R agonists(Interleukin-15 receptors agonists), PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Solid tumor
Originator Organization
GT Biopharma, Inc.GT Biopharma, Inc.
Active Organization-
Inactive Organization
GT Biopharma, Inc.GT Biopharma, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with GTB-4550
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100 Translational Medicine associated with GTB-4550
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100 Patents (Medical) associated with GTB-4550
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100 Deals associated with GTB-4550
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPreclinical
United States
GT Biopharma, Inc.GT Biopharma, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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