Last update 22 Dec 2024

IRAK1/IRAK4/FLT3 inhibitors(National Center for Advancing Translational Sciences)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound 31(National Center for Advancing Translational Sciences)
Target
FLT3 x IRAK1 x IRAK4
Mechanism
FLT3 inhibitors(Tyrosine-protein kinase receptor FLT3 inhibitors), IRAK1 antagonists(Interleukin-1 receptor-associated kinase 1 antagonists), IRAK4 inhibitors(Interleukin-1 receptor-associated kinase 4 inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid Leukemia
Inactive Indication-
Originator Organization
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
Active Organization
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure

Molecular FormulaC21H26FN5O2
InChIKeySPZWEDSSAIAPRC-HOCLYGCPSA-N
CAS Registry2760328-82-1

Related

100 Clinical Results associated with IRAK1/IRAK4/FLT3 inhibitors(National Center for Advancing Translational Sciences)
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100 Translational Medicine associated with IRAK1/IRAK4/FLT3 inhibitors(National Center for Advancing Translational Sciences)
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100 Patents (Medical) associated with IRAK1/IRAK4/FLT3 inhibitors(National Center for Advancing Translational Sciences)
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100 Deals associated with IRAK1/IRAK4/FLT3 inhibitors(National Center for Advancing Translational Sciences)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical
US
National Center for Advancing Translational SciencesNational Center for Advancing Translational Sciences
23 Oct 2024
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Clinical Result

Indication
Phase
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Approval

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Regulation

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