Last update 08 May 2025

VU6022296

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
mGluR4
Action
modulators
Mechanism
mGluR4 modulators(代谢型谷氨酸受体-4调节剂)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic Disease
Active Indication
Parkinson Disease
Inactive Indication-
Originator Organization
Vanderbilt UniversityVanderbilt University
Active Organization
Vanderbilt UniversityVanderbilt University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC12H12BrClN2O2S
InChIKeyBYVAPGOEUAONCD-JTQLQIEISA-N
CAS Registry2763037-45-0

Related

100 Clinical Results associated with VU6022296
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100 Translational Medicine associated with VU6022296
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100 Patents (Medical) associated with VU6022296
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1
Literatures (Medical) associated with VU6022296
01 Apr 2021Bioorganic & Medicinal Chemistry LettersQ4 · MEDICINE
Discovery and optimization of a novel CNS penetrant series of mGlu4 PAMs based on a 1,4-thiazepane core with in vivo efficacy in a preclinical Parkinsonian model
Q4 · MEDICINE
100 Deals associated with VU6022296
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Parkinson DiseasePreclinical
United States
Vanderbilt UniversityVanderbilt University
01 Apr 2021
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Clinical Result

Indication
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Approval

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Regulation

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