Last update 24 Mar 2025

APN-1125

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
APN 1125, APN1125
Target
CHRNA7
Action
agonists
Mechanism
α7 receptor agonists(Neuronal acetylcholine receptor protein alpha-7 subunit agonists)
Therapeutic Areas
Nervous System Diseases
Active Indication-
Inactive Indication
Schizophrenia
Originator Organization
CoMentis, Inc.CoMentis, Inc.
Active Organization-
Inactive Organization
CoMentis, Inc.CoMentis, Inc.
Drug Highest PhaseSuspendedPhase 1/2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with APN-1125
NCT02724917
/ SuspendedPhase 1/2
A Phase 1b/2a, Double-blind, Placebo-controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of APN1125 in Subjects With Schizophrenia
NCT02331433
/ CompletedPhase 1
A Phase 1 Double-blind, Placebo-controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of APN1125 in Healthy Normal Subjects
100 Clinical Results associated with APN-1125
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100 Translational Medicine associated with APN-1125
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100 Patents (Medical) associated with APN-1125
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100 Deals associated with APN-1125
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
SchizophreniaPhase 2
United States
CoMentis, Inc.CoMentis, Inc.
01 Apr 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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