Last update 01 Nov 2024

Ori-C321

Overview

Basic Info

Drug Type
CAR-T
Synonyms
Target
BCMA x GPRC5D
Mechanism
BCMA modulators(B-cell maturation protein modulators), GPRC5D modulators(G-protein coupled receptor family C group 5member D modulators)
Therapeutic Areas
NeoplasmsImmune System DiseasesCardiovascular Diseases+ [2]
Active Indication
Plasma cell myeloma refractoryRelapse multiple myelomaMultiple Myeloma
Inactive Indication-
Originator Organization
OriCell Therapeutics Co.,Ltd.OriCell Therapeutics Co.,Ltd.
Active Organization
Zhejiang UniversityZhejiang UniversityOriCell Therapeutics Co.,Ltd.OriCell Therapeutics Co.,Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Ori-C321
NCT05325801 / Not yet recruitingPhase 1IIT
An Open-Label, Dose Finding Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of BMCA and GPRC5D Dual Target CAR-T Cells Therapy in Patients With Relapsed or Refractory Multiple Myeloma
100 Clinical Results associated with Ori-C321
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100 Translational Medicine associated with Ori-C321
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100 Patents (Medical) associated with Ori-C321
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100 Deals associated with Ori-C321
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Plasma cell myeloma refractoryPhase 1-
Zhejiang UniversityZhejiang University
01 Apr 2022
Relapse multiple myelomaPhase 1-
Zhejiang UniversityZhejiang University
01 Apr 2022
Multiple MyelomaIND Application-
OriCell Therapeutics Co.,Ltd.OriCell Therapeutics Co.,Ltd.
-
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Clinical Result

Indication
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Evaluation
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Clinical Trial

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Approval

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Regulation

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