Last update 01 Nov 2025

KPT-355

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
KPT-355
Target
XPO1
Action
inhibitors
Mechanism
XPO1 inhibitors(Exportin-1 protein inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesInfectious Diseases+ [1]
Active Indication-
Inactive Indication
Autoimmune DiseasesInflammationNeoplasms+ [1]
Originator Organization
Karyopharm Therapeutics, Inc.Karyopharm Therapeutics, Inc.
Active Organization-
Inactive Organization
Rega Institute for Medical ResearchKaryopharm Therapeutics, Inc.Karyopharm Therapeutics, Inc.
License Organization-
Drug Highest PhaseDiscontinuedDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with KPT-355
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100 Translational Medicine associated with KPT-355
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100 Patents (Medical) associated with KPT-355
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100 Deals associated with KPT-355
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Autoimmune DiseasesDiscovery
United States
Karyopharm Therapeutics, Inc.Karyopharm Therapeutics, Inc.
-
Autoimmune DiseasesDiscovery
Belgium
Rega Institute for Medical Research
-
InflammationDiscovery
United States
Karyopharm Therapeutics, Inc.Karyopharm Therapeutics, Inc.
-
InflammationDiscovery
Belgium
Rega Institute for Medical Research
-
NeoplasmsDiscovery
United States
Karyopharm Therapeutics, Inc.Karyopharm Therapeutics, Inc.
-
NeoplasmsDiscovery
United States
Rega Institute for Medical Research
-
Virus DiseasesDiscovery
United States
Karyopharm Therapeutics, Inc.Karyopharm Therapeutics, Inc.
-
Virus DiseasesDiscovery
Belgium
Rega Institute for Medical Research
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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