Last update 08 May 2025

SA-7-49

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms-
Target
Top I x Trop-2
Action
inhibitors
Mechanism
TOP1 inhibitors(DNA topoisomerase I inhibitors), Trop-2 inhibitors(Tumor-associated calcium signal transducer 2 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Pancreatic Ductal Adenocarcinoma
Inactive Indication-
Originator Organization
Shanghaitech UniversityShanghaitech University
Active Organization
Shanghaitech UniversityShanghaitech University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with SA-7-49
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100 Translational Medicine associated with SA-7-49
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100 Patents (Medical) associated with SA-7-49
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1
Literatures (Medical) associated with SA-7-49
01 Mar 2025European Journal of Medicinal Chemistry
Exploiting synthetic lethality in PDAC with antibody drug conjugates and ATR inhibition
100 Deals associated with SA-7-49
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic Ductal AdenocarcinomaPreclinical
China
Shanghaitech UniversityShanghaitech University
01 Mar 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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