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Clinical Trials associated with 23-valent pneumococcal polysaccharide vaccine(Chengdu Institute of Biological Products)Immunogenicity and Safety of Quadrivalent Influenza Vaccine Combined Immunization With 23-valent Pneumococcal Polysaccharide Vaccine in the Elderly Aged 60 Years and Above
This study is an open-label,single center phase Ⅳ clinical trial of combined immunization with quadrivalent influenza vaccine and 23-valent pneumococcal polysaccharide vaccine.The purpose of this study is to evaluate the safety and immunogenicity of combined immunization with quadrivalent influenza vaccine and 23-valent pneumococcal polysaccharide vaccine in the elderly aged 60 years and above.
A Randomized, Controlled, Multicenter Phase 4 Clinic Trial to Evaluate the Immunogenicity and Safety of Combined Immunization of Inactivated SARS-CoV-2 Vaccines (Vero Cell) (COVAX) (Produced in Wuhan) and 23-valent Pneumococcal Polysaccharide Vaccine (PPV23) or Quadrivalent Inactivated Influenza Vaccine (IIV4)
Subjects will be recruited and divided into 3 groups:
Experimental Group (468 subjects): 1st dose : combined vaccination of COVAX+PPV23, 2nd dose: combined vaccination of COVAX+IIV4; Control Group A (468 subjects): 1st dose: COVAX only, 2nd dose: COVAX only; Control Group B (468 subjects): 1st dose: PPV23 only, 2nd dose: IIV4 only.
Blood samples will be collected 3 times:
before the 1st dose of vaccinatioin; before the 2nd dose of vaccination; 28 days after the 2nd dose of vaccination.
The immunogenicity and safety of both experimental and control groups will be analyzed.
A randomized, controlled, multi-center clinical study to evaluate the immunogenicity and safety of the new coronavirus inactivated vaccine and the 23-valent pneumococcal polysaccharide vaccine and the quadrivalent influenza virus split vaccine at the same time
Start Date06 May 2021 |
Sponsor / Collaborator- |
100 Clinical Results associated with 23-valent pneumococcal polysaccharide vaccine(Chengdu Institute of Biological Products)
100 Translational Medicine associated with 23-valent pneumococcal polysaccharide vaccine(Chengdu Institute of Biological Products)
100 Patents (Medical) associated with 23-valent pneumococcal polysaccharide vaccine(Chengdu Institute of Biological Products)
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Literatures (Medical) associated with 23-valent pneumococcal polysaccharide vaccine(Chengdu Institute of Biological Products)Correction: Limited indirect effects of an infant pneumococcal vaccination program in an aging population
Q3 · CROSS-FIELD
OA
Author: Perniciaro, Stephanie ; Imöhl, Matthias ; van der Linden, Mark
[This corrects the article DOI: 10.1371/journal.pone.0220453.].
100 Deals associated with 23-valent pneumococcal polysaccharide vaccine(Chengdu Institute of Biological Products)