Fine-customized structure and morphol. of the thin-film-composite polyamide membranes (TFC-PA) play an essential role in obtaining high water permeance and solute-solute selectivity.Herein we fabricated a TFC-PA nanofiltration membrane with excellent separation performance by the regulation of the interfacial polymerization process via a resorcin[4]arene-derived hierarchical POPs intermediate layer (RA-POPs).The RA-POPs interlayer was constructed on the PSF substrate surface through in situ covalent assembly by the azo-coupling reaction, followed by the formation of the PA layer on top of this porous layer.The effect of azo-coupling reaction conditions on the morphologies and performance of the prepared TFC-PA-POPs membranes was investigated.The constructed RA-POPs layer interlayer increased the hydrophilicity of the substrates.This hydrophilic RA-POPs interlayer facilitated the uniform distribution of the amine solution and slowed down the PIP diffusion into the organic phase by the supramol. interactions.Consequently, the formed PA layer exhibited a thinner thickness, a high degree of crosslinking, a crumpled structure and an enhanced neg. charged surface.The obtained TFC-PA-POPs membranes possessed high water permeance of 21.0 L m^-2 h^-1 bar^-1, comparable Na₂SO₄ rejection of 99.35 % and excellent mixed ion selectivity (Cl^-/SO^2-₄) of 340 in the high salt concentration, which is superior to the com. and the state-of-the-art polyamide-based NF membranes.The reduced pore size, narrowed pore size distribution and enhanced surface neg. charge endowed the TFC-PA-POPs membranes with high mono/multivalent anions selectivity.Our approach for modulating the polyamide microstructure by incorporating macrocycle-derived hierarchical porous organic polymer interlayer has provided insight into the design of TFC-PA NF membranes with high water permeance and precise ion separation for high-salinity wastewater treatment and water purification

01 May 2025·Journal of Organometallic Chemistry

Comparative electrochemiluminescence studies about bis-tridentate iridium(III) complexes comprising N heterocyclic carbene

Author: Xu, Yaoyao ; Deng, Rongxiu ; Zhu, Fangming ; Mao, Ziwang ; Dai, Chenji ; Zhou, Yuyang ; Ke, Libing

Exploring novel efficient electrochemiluminescent (ECL) dyes derived from transition metal complexes with new skeletons is always one of the hot and important topics of ECL-related studies.Herein, three bis-tridentate iridium(III) complexes (BisLT-Ir-NHC-R, where R represents H, CH₃ and CF₃) with N-heterocyclic carbenes (NHC) ligands have been prepared in this work.Beside photophysics (PL), theor. calculations and cyclic voltammetry (CV), ECL properties have been comparatively investigated in this work.Notably, not only did the BisLT-Ir-NHC- CF₃ have the highest photoluminescence efficiency value of 13.26%, but most importantly, the ECL efficiency of bis-tridentate iridium(III) complexes in this work was up to 3.4 times than the benchmark of Ru(bpy)₂⁺³ under the same exptl. conditions.These results demonstrates that bis-tridentate iridium(III) complexes with NHC ligands have great potential applications in ECL-based anal. technol. and could open a new avenue to develop highly efficient ECL dyes derived from bis-tridentate iridium complexes in the future.

01 Mar 2025·European Polymer Journal

Acetal-functionalized polyurethane adhesives: A path to debonding-on-demand

Author: Tomovic, Zeljko ; Schara, Patrick ; Cristadoro, Anna M. ; Turel, Tankut ; Linnenbrink, Martin

Polyurethanes stand out as remarkably versatile polymers, renowned for their adjustable mech. and thermal characteristics, making them invaluable across various domains, notably in adhesive applications.Yet conventional polyurethane adhesives typically form permanent bonds, and thus debonding is not possible without harming the bonded substrates.In the light of escalating calls for sustainability, the development of polyurethane adhesives with debonding-on-demand capabilities has become paramount.Such innovations facilitate disassembly, repair, exchange, and recycling of bonded materials.Consequently, herein, we integrate three different linear acetal polyols into one-component, polyether-based polyurethane adhesives.These new systems not only exhibit comparable thermal properties and superior adhesive performance to conventional adhesives but also offer debonding-on-demand capabilities.These findings provide a drop-in solution to the limitations of traditional bonding methods and foster a circular economy, underscoring the pivotal role of adhesive technol. in addressing environmental imperatives.

100 Deals associated with Paraldehyde

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KEGG	Wiki	ATC	Drug Bank
D00705	Paraldehyde	N05CC05	DB09117

R&D Status

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Indication	Country/Location	Organization	Date
Agitation	Australia	Phebra Pty Ltd.	31 Aug 2009
Alcohol Withdrawal Delirium	Australia	Phebra Pty Ltd.	31 Aug 2009
Anxiety Disorders	Australia	Phebra Pty Ltd.	31 Aug 2009
Sedation	Australia	Phebra Pty Ltd.	31 Aug 2009
Seizures	Australia	Phebra Pty Ltd.	31 Aug 2009
Epilepsy	-	-	-
Sleep Initiation and Maintenance Disorders	-	-	-

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