Last update 08 May 2025

CISH inactivated tumor infiltrating lymphocyte cell therapy (Intima Bioscience)

Overview

Basic Info

Drug Type
TIL therapy
Synonyms
Tumor infiltrating lymphocyte cell therapy Intima Bioscience
Target-
Action-
Mechanism
Immunologic cytotoxicity, T lymphocyte replacements
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Colonic CancerEsophageal CarcinomaGallbladder Carcinoma+ [3]
Inactive Indication-
Originator Organization
Intima Bioscience, Inc.Intima Bioscience, Inc.
Active Organization
Intima Bioscience, Inc.Intima Bioscience, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CISH inactivated tumor infiltrating lymphocyte cell therapy (Intima Bioscience)
NCT04426669
/ Active, not recruitingPhase 1/2
A Phase I/II Trial in Patients With Metastatic Gastrointestinal Epithelial Cancer Administering Tumor-Infiltrating Lymphocytes in Which the Gene Encoding CISH Was Inactivated Using the CRISPR/Cas9 System
100 Clinical Results associated with CISH inactivated tumor infiltrating lymphocyte cell therapy (Intima Bioscience)
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100 Translational Medicine associated with CISH inactivated tumor infiltrating lymphocyte cell therapy (Intima Bioscience)
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100 Patents (Medical) associated with CISH inactivated tumor infiltrating lymphocyte cell therapy (Intima Bioscience)
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100 Deals associated with CISH inactivated tumor infiltrating lymphocyte cell therapy (Intima Bioscience)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Colonic CancerPhase 2
United States
Intima Bioscience, Inc.Intima Bioscience, Inc.
15 May 2020
Esophageal CarcinomaPhase 2
United States
Intima Bioscience, Inc.Intima Bioscience, Inc.
15 May 2020
Gallbladder CarcinomaPhase 2
United States
Intima Bioscience, Inc.Intima Bioscience, Inc.
15 May 2020
Metastatic Digestive System CarcinomaPhase 2
United States
Intima Bioscience, Inc.Intima Bioscience, Inc.
15 May 2020
Pancreatic CancerPhase 2
United States
Intima Bioscience, Inc.Intima Bioscience, Inc.
15 May 2020
Stomach CancerPhase 2
United States
Intima Bioscience, Inc.Intima Bioscience, Inc.
15 May 2020
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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