Last update 24 Jan 2026

KNP 502

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
KNP 502, KNP-502, OCT-3598
+ [1]
Target
EP2 x EP4
Action
antagonists
Mechanism
EP2 antagonists(Prostanoid EP2 receptor antagonists), EP4 antagonists(Prostanoid EP4 receptor antagonists)
Therapeutic Areas
NeoplasmsDigestive System DisordersRespiratory Diseases+ [2]
Active Indication
Advanced Malignant Solid NeoplasmGastrooesophageal junction cancerHead and Neck Neoplasms+ [4]
Inactive Indication-
Originator Organization
Kanaph Therapeutics, Inc.Kanaph Therapeutics, Inc.
Active Organization
Samsung Medical CenterSamsung Medical CenterOscotec, Inc.Oscotec, Inc.
Inactive Organization
Kanaph Therapeutics, Inc.Kanaph Therapeutics, Inc.
License Organization
Kanaph Therapeutics, Inc.Kanaph Therapeutics, Inc.
Oscotec, Inc.Oscotec, Inc.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with KNP 502
NCT07358806
/ RecruitingPhase 1
A Phase 1 Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of OCT-598 as a Single Agent and in Combination With Standard-of-Care Treatment in Patients With Advanced Solid Tumors
100 Clinical Results associated with KNP 502
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100 Translational Medicine associated with KNP 502
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100 Patents (Medical) associated with KNP 502
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100 Deals associated with KNP 502
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
South Korea
Oscotec, Inc.Oscotec, Inc.
18 Dec 2025
Gastrooesophageal junction cancerPhase 1
South Korea
Oscotec, Inc.Oscotec, Inc.
18 Dec 2025
Head and Neck NeoplasmsPhase 1
South Korea
Oscotec, Inc.Oscotec, Inc.
18 Dec 2025
Human epidermal growth factor 2 negative carcinoma of breastPhase 1
South Korea
Oscotec, Inc.Oscotec, Inc.
18 Dec 2025
Non-Small Cell Lung CancerPhase 1
South Korea
Oscotec, Inc.Oscotec, Inc.
18 Dec 2025
Prostatic CancerPhase 1
South Korea
Oscotec, Inc.Oscotec, Inc.
18 Dec 2025
Solid tumorPreclinical
South Korea
Kanaph Therapeutics, Inc.Kanaph Therapeutics, Inc.
19 Dec 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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