Last update 08 Aug 2026

DNTH-312

Overview

Basic Info

Drug Type
Antibody fusion proteins
Synonyms
Claseprubart and TACI bifunctional fusion protein, DNTH 312, DNTH312
Target
C1S x TACI
Action
inhibitors
Mechanism
C1S inhibitors(Complement C1s inhibitors), TNFRSF13B inhibitors(Tumor necrosis factor receptor superfamily member 13B inhibitors)
Therapeutic Areas
Immune System Diseases
Active Indication
Autoimmune Diseases
Inactive Indication-
Originator Organization
Dianthus Therapeutics, Inc.Dianthus Therapeutics, Inc.
Active Organization
Dianthus Therapeutics, Inc.Dianthus Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with DNTH-312
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100 Translational Medicine associated with DNTH-312
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100 Patents (Medical) associated with DNTH-312
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100 Deals associated with DNTH-312
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Autoimmune DiseasesPreclinical
United States
Dianthus Therapeutics, Inc.Dianthus Therapeutics, Inc.
01 Aug 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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