Delving into the Latest Updates on CHO-A04 with Synapse

Overview

Basic Info

Drug Type

Monoclonal antibody

Synonyms-

Target

SSEA-4

Action

inhibitors

Mechanism

SSEA-4 inhibitors(Stage-specific embryonic antigen-4 inhibitors)

Therapeutic Areas

Neoplasms

Active Indication

Locally Advanced Malignant Solid NeoplasmNeoplasms

Inactive Indication-

Originator Organization

Academia Sinica

Active Organization

Academia Sinica

CHO Pharma, Inc.

Inactive Organization-

License Organization-

Drug Highest PhasePhase 1/2

First Approval Date-

Regulation-

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The goal of this clinical trial is to learn if the study drug, CHO-A04, works to treat solid cancers in adults. It will also aim to learn about the safety of CHO-A04 and find the best dose to use in future cancer treatment. The main questions it aims to answer are:
* Which dose of CHO-A04 shows the best anti-cancer ability?
* How will your body respond to CHO-A04 treatment?
* How long will CHO-A04 remain in your body?
There are two stages of investigation in this study:
* Phase I: to find the best anti-cancer dose of CHO-A04
* Phase IIa: to find the CHO-A04 anti-cancer ability in specific cancer types
In this study, each participant will be assigned to one of the CHO-A04 dose levels. Participants will have CHO-A04 infusion via blood vessel once every week for four weeks. The CHO-A04 treatment may continue based on participants' condition and CHO-A04 safety evaluations.

Start Date01 Dec 2025

Sponsor / Collaborator

CHO Pharma, Inc.

100 Clinical Results associated with CHO-A04

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100 Translational Medicine associated with CHO-A04

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100 Patents (Medical) associated with CHO-A04

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100 Deals associated with CHO-A04

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R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Locally Advanced Malignant Solid Neoplasm	Phase 2	Taiwan Province	CHO Pharma, Inc.	01 Dec 2025
Neoplasms	Preclinical	-	Academia Sinica	-

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Clinical Result

Indication

Phase

Evaluation

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

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