Last update 11 Mar 2026

Vascular endothelial growth factor-121 localised protein delivery(GenVec, Inc.)

Overview

Basic Info

Drug Type
Growth factors
Synonyms
BIOBYPASS, BIOBYPASS angiogen, BIOBYPASS-CAD
+ [3]
Target
VEGFR
Action
agonists
Mechanism
VEGFR agonists(Vascular endothelial growth factor receptor agonists)
Therapeutic Areas
Nervous System DiseasesCardiovascular DiseasesOther Diseases
Active Indication-
Inactive Indication
Angina, StableMyocardial IschemiaPeripheral Arterial Disease
Originator Organization
GenVec, Inc.GenVec, Inc.
Active Organization-
Inactive Organization
GenVec, Inc.GenVec, Inc.Cordis Endovascular Systems, Inc.Cordis Endovascular Systems, Inc.
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Vascular endothelial growth factor-121 localised protein delivery(GenVec, Inc.)
NCT00215696
/ CompletedPhase 2
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy of BIOBYPASS® (ADGVVEGF121.10NH) Delivered by NOGA™-GUIDED/MYOSTAR™ Catheter in "No Option" Patients With Class II-IV Stable Angina
100 Clinical Results associated with Vascular endothelial growth factor-121 localised protein delivery(GenVec, Inc.)
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100 Translational Medicine associated with Vascular endothelial growth factor-121 localised protein delivery(GenVec, Inc.)
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100 Patents (Medical) associated with Vascular endothelial growth factor-121 localised protein delivery(GenVec, Inc.)
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100 Deals associated with Vascular endothelial growth factor-121 localised protein delivery(GenVec, Inc.)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Angina, StablePhase 2
Denmark
GenVec, Inc.GenVec, Inc.
17 Feb 2005
Myocardial IschemiaPhase 2-
Cordis Endovascular Systems, Inc.Cordis Endovascular Systems, Inc.
-
Peripheral Arterial DiseasePhase 2-
GenVec, Inc.GenVec, Inc.
-
Peripheral Arterial DiseasePhase 2-
Cordis Endovascular Systems, Inc.Cordis Endovascular Systems, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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