Last update 18 Nov 2025

ML345

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
IDE x NLRP3
Action
inhibitors
Mechanism
IDE inhibitors(Insulin degrading enzyme inhibitors), NLRP3 inhibitors(NACHT, LRR and PYD domains-containing protein 3 inhibitors)
Therapeutic Areas
Endocrinology and Metabolic DiseaseOther Diseases
Active Indication
AbortionInflammationDiabetes Mellitus, Type 2
Inactive Indication-
Originator Organization
The Scripps Research InstituteThe Scripps Research Institute
Active Organization
The Scripps Research InstituteThe Scripps Research Institute
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with ML345
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100 Translational Medicine associated with ML345
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100 Patents (Medical) associated with ML345
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100 Deals associated with ML345
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
AbortionPreclinical--14 Nov 2025
InflammationPreclinical--14 Nov 2025
Diabetes Mellitus, Type 2Preclinical
United States
The Scripps Research InstituteThe Scripps Research Institute
13 May 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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