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Clinical Trials associated with TBL-1002OIInsulin Resistance in Non-diabetic Multiple Sclerosis Patients: Prevalence, Pre and Post-treatment Effect on Clinical, Cognitive Profile, Laboratory, and Radiological Markers
The goal of this three-phase interventional study is to determine the prevalence of Insulin resistance in non-diabetic patients with multiple sclerosis in Egypt
The main questions it aims to answer are:
what is the prevalence of insult resistance among Egyptian patients with Multiple sclerosis?
what are the effects of insulin resistance on multiple sclerosis disease activity and progression
what are the effects of treating insulin resistance on multiple sclerosis disease activity and progression participants with MS will be tested for IR to determine its prevalence, in the 2nd phase a group of MS patients with IR will be compared with another control group of MS patients without IR for clinical, laboratory, and radiological markers of disease activity and progression twice at baseline and after 1 year. in the 3rd phase, patients with IR will be divided into 2 groups one who will receive appropriate treatment for IR and the other group without treatment of IR and will be compared by the end of the 2nd year for clinical, laboratory and radiological markers of disease activity and progression
Pilot Study for the Evaluation of Algorithms for the Detection of Subcutaneous Insulin Pump Malfunctions in Subjects With Type 1 Diabetes
The goal of this clinical trial is to test the effectiveness of fault-detection algorithms in detecting malfunctioning of the insulin infusion system in an artificial pancreas (also known as Automated Insulin Delivery system) for type 1 diabetes.
The main questions it aims to answer is:
"Are the proposed algorithms effective in detecting insulin suspension?" Effectiveness accounts for both high sensitivity (i.e. the fraction of suspension correctly detected) and low false alarm rate.
The study has three phases:
free-living artificial pancreas data collection,
in-patient induction of hyperglycemia (mimicking an insulin pump malfunction),
retrospective analysis of the collected data to evaluate the effectiveness of the proposed algorithms in detecting insulin suspension.
Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars
Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.
100 Clinical Results associated with TBL-1002OI
100 Translational Medicine associated with TBL-1002OI
100 Patents (Medical) associated with TBL-1002OI
100 Deals associated with TBL-1002OI