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Last update 08 May 2025
HSK-29116
Last update 08 May 2025
Overview
Basic Info
Drug Type Proteolysis-targeting chimeras (PROTAC) |
Synonyms |
Target |
Action inhibitors |
Mechanism BTK inhibitors(Tyrosine-protein kinase BTK inhibitors), Proteolysis |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with HSK-29116CTR20233200
一项评价HSK29116在复发或难治性B细胞恶性肿瘤受试者中的初步安全性和有效性的、剂量扩展I期临床研究
[Translation] A Phase I dose-expansion study evaluating the safety and efficacy of HSK29116 in subjects with relapsed or refractory B-cell malignancies
NCT04861779
A Phase Ia/b Clinical Study on Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of BTK Protein Degradation Agent HSK29116 in Subjects With Relapsed or Refractory B-Cell Malignancy
CTR20210774
一项评价BTK蛋白降解剂 HSK29116在复发或难治性B细胞恶性肿瘤受试者中的安全性、耐受性和药代动力学/药效学的Ia/b期临床研究
[Translation] A Phase Ia/b study evaluating the safety, tolerability, and pharmacokinetics/pharmacodynamics of HSK29116, a BTK protein degrader, in subjects with relapsed or refractory B-cell malignancies
100 Clinical Results associated with HSK-29116
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100 Translational Medicine associated with HSK-29116
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100 Patents (Medical) associated with HSK-29116
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100 Deals associated with HSK-29116
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| B-Cell Lymphoma | Phase 1 | United States | 14 Apr 2022 | |
| B-Cell Malignant Neoplasm | Phase 1 | China | 30 Jul 2021 | |
| Neoplasms | Preclinical | China | 24 Aug 2021 | |
| Neoplasms | Preclinical | Australia | 24 Aug 2021 |
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