Drug Type Bispecific antibody |
Synonyms anti-CLDN6-CD137 BsAb, NBL 028, NBL-028 |
Target |
Action agonists, modulators |
Mechanism 4-1BB agonists(Tumor necrosis factor receptor superfamily member 9 agonists), CLDN6 modulators(Claudin 6 modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 1 | China | 08 Mar 2024 | |
| CLDN6-positive Solid Tumors | IND Approval | China | 24 Oct 2023 | |
| Stomach Cancer | IND Approval | China | 24 Oct 2023 | |
| Endometrial Carcinoma | IND Approval | United States | 18 Aug 2023 | |
| Non-Small Cell Lung Cancer | IND Approval | United States | 18 Aug 2023 | |
| Ovarian Cancer | IND Approval | United States | 18 Aug 2023 | |
| Testicular Neoplasms | IND Approval | United States | 18 Aug 2023 |






