Last update 08 May 2025

Pioglitazone Hydrochloride/Sitagliptin Phosphate Monohydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Janacti, Pioglitazine/sitagliptin, Sitagliptin/pioglitazone
+ [2]
Target
DPP-4 x PPARγ
Action
inhibitors, agonists
Mechanism
DPP-4 inhibitors(Dipeptidyl peptidase IV inhibitors), PPARγ agonists(Peroxisome proliferator-activated receptor γ agonists)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Diabetes Mellitus, Type 2
Originator Organization
Merck & Co., Inc.Merck & Co., Inc.
Active Organization-
Inactive Organization
Merck GmbHMerck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
License Organization-
Drug Highest PhaseDiscontinuedNDA/BLA
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H21ClN2O3S
InChIKeyGHUUBYQTCDQWRA-UHFFFAOYSA-N
CAS Registry112529-15-4
View All Structures (2)

Related

100 Clinical Results associated with Pioglitazone Hydrochloride/Sitagliptin Phosphate Monohydrate
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100 Translational Medicine associated with Pioglitazone Hydrochloride/Sitagliptin Phosphate Monohydrate
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100 Patents (Medical) associated with Pioglitazone Hydrochloride/Sitagliptin Phosphate Monohydrate
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100 Deals associated with Pioglitazone Hydrochloride/Sitagliptin Phosphate Monohydrate
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2NDA/BLA
European Union
Merck GmbH
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
ADA2021
Not Applicable
-
20
fyjxqidpru(wslnvhcgyv) = gimdhqnmtr ckyisuzjqx (nescybhfvd )
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-
01 Jun 2021
Placebo
fyjxqidpru(wslnvhcgyv) = ydyqnbwenh ckyisuzjqx (nescybhfvd )
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Deal

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Approval

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Regulation

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