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Last update 06 Jan 2026
Gliclazide/Metformin Hydrochloride
Last update 06 Jan 2026
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms 二甲双胍格列齐特 |
Target |
Action activators, agonists |
Mechanism PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators), SUR agonists(Sulfonylurea receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (22 Sep 2005), |
Regulation- |
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Structure/Sequence
Molecular FormulaC15H21N3O3S |
InChIKeyBOVGTQGAOIONJV-UHFFFAOYSA-N |
CAS Registry21187-98-4 |
View All Structures (2)
Related
6
Clinical Trials associated with Gliclazide/Metformin HydrochlorideCTR20202686
二甲双胍格列吡嗪片单中心、开放、随机、单剂量、两周期、两序列、交叉生物等效性研究
[Translation] A single-center, open-label, randomized, single-dose, two-period, two-sequence, crossover bioequivalence study of metformin and glipizide tablets
NCT03467971
A Randomized, Open-label, Single Dose, 2x2 Crossover Trial to Evaluate the Food Effect on the Bioavailability of a Metformin/Gliclazide Fixed Combination Tablet (1000 mg /30 mg MR) Given in Fasting and Fed Conditions to Healthy Volunteers
NCT03467945
Randomized, Open Label, Single Dose, 4 Treatment, 4 Period, Crossover Design (4 x 4) Trial to Evaluate the Bioequivalence and Secondarily Drug - Drug Interaction of Fixed Combination of Metformin Tablets 1000 mg/Gliclazide 30 mg MR, Compared With the Co-administration of Individual Tablets and Individual Administration of Each Single Tablet (Metformin 1000 mg XR and Gliclazide 30 mg MR) in Healthy Volunteers
100 Clinical Results associated with Gliclazide/Metformin Hydrochloride
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100 Translational Medicine associated with Gliclazide/Metformin Hydrochloride
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100 Patents (Medical) associated with Gliclazide/Metformin Hydrochloride
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100 Deals associated with Gliclazide/Metformin Hydrochloride
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R&D Status
10 top approved records. to view more data
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Diabetes Mellitus, Type 2 | China | 22 Sep 2005 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1 | - | 21 | Metformin+Gliclazide (Metformin-Gliclazide (Fasted)) | ycncrbjuek(emetugsluk) = kpdlchvapx zitdjwgjlr (hnspemcqvm, 1599.3290) View more | - | 08 Jul 2019 | |
Metformin+Gliclazide (Metformin-Gliclazide (Fed)) | ycncrbjuek(emetugsluk) = dmgnlcfzvd zitdjwgjlr (hnspemcqvm, 2544.6658) View more |
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