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Last update 29 Jul 2025
PF-08046876
Last update 29 Jul 2025
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms- |
Target |
Action inhibitors |
Mechanism ITGB6 inhibitors(integrin subunit beta 6 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
Structure/Sequence
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Adenocarcinoma of Esophagus | Phase 1 | - | 07 Aug 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 1 | - | 07 Aug 2025 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | - | 07 Aug 2025 | |
| Bladder Cancer | Phase 1 | - | 07 Aug 2025 | |
| Esophageal Squamous Cell Carcinoma | Phase 1 | - | 07 Aug 2025 | |
| Gastroesophageal junction adenocarcinoma | Phase 1 | - | 07 Aug 2025 | |
| Pancreatic adenocarcinoma | Phase 1 | - | 07 Aug 2025 | |
| Squamous Cell Carcinoma of Head and Neck | Phase 1 | - | 07 Aug 2025 | |
| Urothelial Carcinoma of the Urinary Bladder | Phase 1 | - | 07 Aug 2025 | |
| Non-Small Cell Lung Cancer | Preclinical | United States | 28 Apr 2025 |
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Clinical Result
Clinical Result
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Biosimilar
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Regulation
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