Last update 20 May 2025

PF-08046876

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms-
Target
ITGB6 x Top I
Action
inhibitors
Mechanism
ITGB6 inhibitors(integrin subunit beta 6 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Non-Small Cell Lung CancerPancreatic CancerSquamous Cell Carcinoma of Head and Neck+ [1]
Inactive Indication-
Originator Organization
Pfizer Inc.Pfizer Inc.
Active Organization
Pfizer Inc.Pfizer Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with PF-08046876
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100 Translational Medicine associated with PF-08046876
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100 Patents (Medical) associated with PF-08046876
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100 Deals associated with PF-08046876
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPreclinical
United States
Pfizer Inc.Pfizer Inc.
28 Apr 2025
Pancreatic CancerPreclinical
United States
Pfizer Inc.Pfizer Inc.
28 Apr 2025
Squamous Cell Carcinoma of Head and NeckPreclinical
United States
Pfizer Inc.Pfizer Inc.
28 Apr 2025
Transitional Cell CarcinomaPreclinical
United States
Pfizer Inc.Pfizer Inc.
28 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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