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Last update 21 Mar 2025
BrAD-R13
Last update 21 Mar 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms 7,8-dihydroxyflayone derivative (Shanghai Braegen Pharmaceutical), BRAD R13, BRAD-R13 + [2] |
Target |
Action stimulants |
Mechanism TrkB stimulants(Neurotrophic tyrosine kinase receptor type 2 stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with BrAD-R13ChiCTR2300078487
Evaluation of the safety, tolerability, and pharmacokinetics of BrAD-R13 in healthy Chinese subjects: a single center, randomized, double-blind, single dose, and multiple dose study
CTR20233658
评估在中国健康受试者进行的单中心、随机、双盲、单次、多次给药BrAD-R13的安全性、耐受性和药代动力学特征、食物影响和物质平衡研究。
[Translation] A single-center, randomized, double-blind, single- and multiple-dose study of BrAD-R13 was conducted in healthy Chinese subjects to evaluate its safety, tolerability, pharmacokinetic characteristics, food effects, and material balance.
100 Clinical Results associated with BrAD-R13
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100 Translational Medicine associated with BrAD-R13
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100 Patents (Medical) associated with BrAD-R13
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2
Literatures (Medical) associated with BrAD-R1301 Aug 1978Cancer research
Competitive binding and metabolism of several carcinogenic polycyclic aromatic hydrocarbons by AKR mouse embryo cells in culture.
Article
Author: Spelsberg, T C ; Zytkovicz, T H ; Moses, H L
01 Mar 1978Laboratory investigation; a journal of technical methods and pathology
Metabolism of [3H]benzo[a]pyrene by cultured human bronchus and cultured human pulmonary alveolar macrophages.
Article
Author: Schafer, P W ; Stoner, G D ; Harris, C C ; Autrup, H ; Trump, B F ; Selkirk, J K
100 Deals associated with BrAD-R13
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Alzheimer Disease | Phase 1 | United States | 01 May 2019 | |
| Schizophrenia | Preclinical | China | 29 Aug 2024 | |
| Amyotrophic Lateral Sclerosis | Preclinical | China | 11 May 2024 | |
| ischemic brain injury | Preclinical | China | 11 May 2024 | |
| Acute Ischemic Stroke | Preclinical | - | - | |
| Depressive Disorder | Preclinical | China | - | |
| Parkinson Disease | Preclinical | China | - |
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