Last update 20 Mar 2025

AAV-mxABE-Myo6

Overview

Basic Info

Drug Type
Gene editing
Synonyms
dCas13X-RNA碱基编辑器（mxABE）, dCas13X-derived RNA base editor
Target
MYO6
Action
modulators
Mechanism
MYO6 modulators(myosin VI modulators)
Therapeutic Areas
Nervous System DiseasesOtorhinolaryngologic Diseases
Active Indication
Hearing Disorders
Inactive Indication-
Originator Organization
Shanghai Institute of Nutrition and Health, Chinese Academy of SciencesShanghai Institute of Nutrition and Health, Chinese Academy of SciencesHuidaGene Therapeutics Co., Ltd.HuidaGene Therapeutics Co., Ltd.Startup
Active Organization
Shanghai Institute of Nutrition and Health, Chinese Academy of SciencesShanghai Institute of Nutrition and Health, Chinese Academy of SciencesHuidaGene Therapeutics Co., Ltd.HuidaGene Therapeutics Co., Ltd.Startup
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
RegulationRare Pediatric Disease (United States), Orphan Drug (United States)

Related

100 Clinical Results associated with AAV-mxABE-Myo6
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100 Translational Medicine associated with AAV-mxABE-Myo6
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100 Patents (Medical) associated with AAV-mxABE-Myo6
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1
Literatures (Medical) associated with AAV-mxABE-Myo6
20 Jul 2022Science Translational MedicineQ1 · MEDICINE
Rescue of autosomal dominant hearing loss by in vivo delivery of mini dCas13X-derived RNA base editor
Q1 · MEDICINE
100 Deals associated with AAV-mxABE-Myo6
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hearing DisordersPreclinical
China
HuidaGene Therapeutics Co., Ltd.HuidaGene Therapeutics Co., Ltd.Startup
20 Jul 2022
Hearing DisordersPreclinical
China
Shanghai Institute of Nutrition and Health, Chinese Academy of SciencesShanghai Institute of Nutrition and Health, Chinese Academy of Sciences
20 Jul 2022
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Clinical Result

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Regulation

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