Last update 25 Apr 2026

CR-059

Overview

Basic Info

Drug Type
circular RNA, Liposomal Drug
Synonyms
Exenatide Circular RNA-Lipid Nanoparticle Injection, CR-059
Target
GLP-1R
Action
agonists
Mechanism
GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication
Diabetes Mellitus, Type 2
Inactive Indication-
Originator Organization
PegBio Co., Ltd.PegBio Co., Ltd.
Active Organization
PegBio Co., Ltd.PegBio Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with CR-059
NCT07347080
/ RecruitingEarly Phase 1IIT
A Single-Center, Open-Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects With Type 2 Diabetes Mellitus
ChiCTR2600116060
/ Not yet recruitingEarly Phase 1IIT
A Single-Center, Open-Label, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Exenatide Circular RNA-Lipid Nanoparticle Injection (CR059) in Chinese Subjects with Type 2 Diabetes Mellitus
100 Clinical Results associated with CR-059
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100 Translational Medicine associated with CR-059
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100 Patents (Medical) associated with CR-059
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100 Deals associated with CR-059
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 1
China
PegBio Co., Ltd.PegBio Co., Ltd.
20 Jan 2026
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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