Last update 27 Jan 2026

Charis 1000

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
C 1K, C1K, CHARIS1000
Target
TGF-β1
Action
inhibitors
Mechanism
TGF-β1 inhibitors(Transforming growth factor beta 1 inhibitors)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Solid tumorTriple Negative Breast Cancer
Inactive Indication-
Originator Organization
Ensol Biosciences, Inc.Ensol Biosciences, Inc.
Active Organization
Ensol Biosciences, Inc.Ensol Biosciences, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with Charis 1000
NCT05701644
/ CompletedPhase 1
A Dose-block Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose, First-in-human, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects
KCT0008074
/ Not yet recruitingPhase 1
A dose-block randomized, double-blind, placebo-controlled, single and multiple ascending dose, first-in-human, phase 1 clinical trial to evaluate the safety, tolerability, and pharmacokinetics after subcutaneous administration of C1K in healthy subjects
100 Clinical Results associated with Charis 1000
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100 Translational Medicine associated with Charis 1000
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100 Patents (Medical) associated with Charis 1000
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100 Deals associated with Charis 1000
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 1
South Korea
Ensol Biosciences, Inc.Ensol Biosciences, Inc.
-
Triple Negative Breast CancerPreclinical
South Korea
Ensol Biosciences, Inc.Ensol Biosciences, Inc.
15 Jun 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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