1
Clinical Trials associated with BGC-0228注射用BGC0228治疗晚期实体肿瘤的I期临床研究
[Translation] Phase I clinical study of BGC0228 for injection in the treatment of advanced solid tumors
主要目的:在经标准治疗失败(疾病进展或无法耐受)或缺乏标准治疗的晚期实体肿瘤患者中确定注射用BGC0228的最大耐受剂量(MTD)或II期推荐剂量(RP2D)及安全性。
次要目的:探索注射用BGC0228单药治疗在单次和多次给药条件下在晚期实体肿瘤患者中的药代动力学(PK)特征;初步评价注射用BGC0228单药治疗晚期实体肿瘤(如胰腺癌、结直肠癌、卵巢癌、胃癌、食管癌、乳腺癌、非小/小细胞肺癌等)患者的临床疗效。
[Translation] Primary objective: To determine the maximum tolerated dose (MTD) or Phase II recommended dose (RP2D) and safety of BGC0228 for injection in patients with advanced solid tumors who have failed standard treatment (disease progression or intolerance) or lack standard treatment.
Secondary objective: To explore the pharmacokinetic (PK) characteristics of BGC0228 for injection monotherapy in patients with advanced solid tumors under single and multiple dosing conditions; to preliminarily evaluate the clinical efficacy of BGC0228 for injection monotherapy in patients with advanced solid tumors (such as pancreatic cancer, colorectal cancer, ovarian cancer, gastric cancer, esophageal cancer, breast cancer, non-small/small cell lung cancer, etc.).
100 Clinical Results associated with BGC-0228
100 Translational Medicine associated with BGC-0228
100 Patents (Medical) associated with BGC-0228
100 Deals associated with BGC-0228