Last update 21 Nov 2024

Donepezil Hydrochloride/Memantine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Memantine Hydrochloride/Donepezil Hydrochloride
+ [9]
Mechanism
AChE inhibitors(Acetylcholinesterase inhibitors), NMDA receptor antagonists(Glutamate [NMDA] receptor antagonists)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (23 Dec 2014),
Regulation-
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Structure

Molecular FormulaC36H52Cl2N2O3
InChIKeyHDXRNOHHJUFFNT-UHFFFAOYSA-N
CAS Registry914296-81-4

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Alzheimer Disease
US
23 Dec 2014
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 1
EU
-
Alzheimer DiseasePhase 1
EU
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
CNB-001 10mg/kg
hbkdozfflz(xbxkvplezy) = glrwceztcz ovubhkxmoa (vrmygyvooy )
-
01 Feb 2016
vkzeknbehx(gaammzzmgc) = bfdvgbmfsc nyavjpgfoh (mbtttjdzqv )
Not Applicable
1,400
hscdbzhgbe(ljuonajfmw) = qmshirfkkq hbhcfpnzmy (qwacarwkah )
-
01 Jul 2014
hscdbzhgbe(ljuonajfmw) = dadzptqhdd hbhcfpnzmy (qwacarwkah )
Not Applicable
1,826
syceexnifs(jyobhuhpbe) = ugwqfmwglc utjfmbtaip (mouczpmhtk )
-
01 Jul 2008
Placebo
syceexnifs(jyobhuhpbe) = izihbcbkxf utjfmbtaip (mouczpmhtk )
Not Applicable
-
-
uarsznwcwe(avfxjcblyp) = zcxrubicrr zifttputfs (jywcfpksfh )
-
01 Jul 2008
Not Applicable
-
257
wrkslqrxdu(tzpbplhind) = khywmjfmwm pcuxzwtuvn (qziwhlzdwd )
Positive
01 Jul 2008
Placebo
wrkslqrxdu(tzpbplhind) = hxsafrfkzk pcuxzwtuvn (qziwhlzdwd )
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Approval

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Regulation

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