Human Granulocyte Colony-stimulating factor(North China Pharmaceutical Genetech Biotechnology)

Using 1.0mL; 300ug recombinant human granulocyte-stimulating factor injection (rhG-CSF) as the test preparation, a comparative study was conducted with 1.2mL: 300ug rhG-CSF (reference preparation) in accordance with the relevant provisions of the bioequivalence study, to investigate the pharmacokinetic (PK) characteristics/pharmacodynamic (PD) characteristics of a single subcutaneous injection of the test preparation or the reference preparation of rhG-CSF in Chinese healthy subjects, and to evaluate the bioequivalence and safety of the two preparations.