Last update 28 Feb 2026

ABSK-141

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ABSK 141, ABSK141
Target
KRAS G12D
Action
inhibitors
Mechanism
KRAS G12D inhibitors(GTPase KRas G12D inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
KRAS G12D mutation Solid TumorsLocally Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Abbisko Therapeutics Co., Ltd.Abbisko Therapeutics Co., Ltd.
Active Organization
Abbisko Therapeutics Co., Ltd.Abbisko Therapeutics Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with ABSK-141
NCT07417189
/ Not yet recruitingPhase 1/2
A Phase I/II, Open-Label Study of ABSK141 to Assess Safety, Tolerability, Efficacy and Pharmacokinetics in Patients With KRAS G12D Mutant Advanced Solid Tumors
100 Clinical Results associated with ABSK-141
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100 Translational Medicine associated with ABSK-141
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100 Patents (Medical) associated with ABSK-141
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100 Deals associated with ABSK-141
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
KRAS G12D mutation Solid TumorsPhase 2
China
Abbisko Therapeutics Co., Ltd.Abbisko Therapeutics Co., Ltd.
20 Mar 2026
Locally Advanced Malignant Solid NeoplasmPhase 2
China
Abbisko Therapeutics Co., Ltd.Abbisko Therapeutics Co., Ltd.
20 Mar 2026
NeoplasmsDiscovery
China
Abbisko Therapeutics Co., Ltd.Abbisko Therapeutics Co., Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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