Last update 24 Mar 2025

GT-919

Overview

Basic Info

Drug Type
Degradable Molecular Glue
Synonyms
GT 919, GT-919, GT919
Target
IKZF1 x IKZF3
Action
inhibitors
Mechanism
IKZF1 inhibitors(DNA-binding protein Ikaros inhibitors), IKZF3 inhibitors(Zinc finger protein Aiolos inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [3]
Active Indication
Hematologic NeoplasmsMultiple MyelomaPOEMS Syndrome
Inactive Indication-
Originator Organization
Gluetacs Therapeutics (Shanghai) Co., Ltd.Gluetacs Therapeutics (Shanghai) Co., Ltd.
Active Organization
Gluetacs Therapeutics (Shanghai) Co., Ltd.Gluetacs Therapeutics (Shanghai) Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with GT-919
CTR20231255
/ RecruitingPhase 1
评估GT919在恶性血液肿瘤患者中的安全性、耐受性、药代动力学特征及初步疗效的I期临床研究
[Translation] A Phase I clinical study to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of GT919 in patients with malignant hematological tumors
100 Clinical Results associated with GT-919
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100 Translational Medicine associated with GT-919
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100 Patents (Medical) associated with GT-919
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100 Deals associated with GT-919
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hematologic NeoplasmsPhase 1
China
Gluetacs Therapeutics (Shanghai) Co., Ltd.Gluetacs Therapeutics (Shanghai) Co., Ltd.
03 Jul 2023
Multiple MyelomaPhase 1
China
Gluetacs Therapeutics (Shanghai) Co., Ltd.Gluetacs Therapeutics (Shanghai) Co., Ltd.
03 Jul 2023
POEMS SyndromeIND Approval
China
Gluetacs Therapeutics (Shanghai) Co., Ltd.Gluetacs Therapeutics (Shanghai) Co., Ltd.
04 Mar 2025
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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