Last update 11 Mar 2025

Ac-225-conjugated anti-HER3 antibody (Actinium Pharmaceuticals)

Overview

Basic Info

Drug Type
Radiolabeled antibody, Therapeutic radiopharmaceuticals
Synonyms
225Ac-HER3 ARC, Ac-225-HER3-ARC, Actinium-225-conjugated anti-HER3 antibody (Actinium Pharmaceuticals)
Target
HER3
Mechanism
HER3 antagonists(Receptor tyrosine-protein kinase erbB-3 antagonists)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Colorectal CancerKidney NeoplasmsOvarian Cancer+ [2]
Inactive Indication-
Originator Organization
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
Active Organization
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Ac-225-conjugated anti-HER3 antibody (Actinium Pharmaceuticals)
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100 Translational Medicine associated with Ac-225-conjugated anti-HER3 antibody (Actinium Pharmaceuticals)
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100 Patents (Medical) associated with Ac-225-conjugated anti-HER3 antibody (Actinium Pharmaceuticals)
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100 Deals associated with Ac-225-conjugated anti-HER3 antibody (Actinium Pharmaceuticals)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPreclinical
US
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
04 Apr 2023
Kidney NeoplasmsPreclinical
US
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
04 Apr 2023
Ovarian CancerPreclinical
US
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
04 Apr 2023
Prostatic CancerPreclinical
US
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
04 Apr 2023
NeoplasmsPreclinical-
Actinium Pharmaceuticals, Inc.Actinium Pharmaceuticals, Inc.
11 Apr 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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