Last update 08 May 2025

Ibuprofen/Pseudoephedrine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound Ibuprofen for Suspension, Ibuprofen and Pseudoephed Hydrochloride Granules, Ibuprofen and Pseudoephedrin Hydrochloride
+ [17]
Target
COXs x α-adrenergic receptor
Action
inhibitors, agonists
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), α-adrenergic receptor agonists(Alpha adrenergic receptor agonists)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesOtorhinolaryngologic Diseases+ [1]
Active Indication
Rhinitis, AllergicSinusitisNasal Obstruction+ [2]
Inactive Indication-
Originator Organization
Pfizer Inc.Pfizer Inc.
Active Organization
Haleon US Capital LLCJohnson & Johnson Pacific Pty Ltd.Johnson & Johnson Pacific Pty Ltd.Hebei Jiheng (Group) Pharmaceutical Co. Ltd.Hebei Jiheng (Group) Pharmaceutical Co. Ltd.
+ [1]
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (19 Sep 1989),
Common ColdInfluenza, Human
Regulation-
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Structure/Sequence

Molecular FormulaC13H18O2
InChIKeyHEFNNWSXXWATRW-UHFFFAOYSA-N
CAS Registry15687-27-1
View All Structures (2)

Related

4
Clinical Trials associated with Ibuprofen/Pseudoephedrine Hydrochloride
NCT03184766
/ CompletedPhase 1
An Open-label, Randomised, Three-way Cross-over, Single Dose, Single Centre, Comparative Pharmacokinetic Study Between Ibuprofen and Pseudoephedrine Liquid Capsules (2x 200 mg Ibuprofen & 30 mg Pseudoephedrine) (Test), Ibuprofen and Pseudoephedrine Tablets (2x 200 mg Ibuprofen & 30 mg Pseudoephedrine) (Comparator 1), and Ibuprofen Liquid Capsules (2x 200 mg Solubilised Ibuprofen) (Comparator 2)
NCT01131780
/ CompletedPhase 1
A Randomized, Open Label, 2-treatment, Single Dose, Crossover, Bioequivalence Study of Ibuprofen 200 mg+Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's and Advil® Cold and Sinus Caplets of Wyeth Consumer Healthcare Under Fasting Conditions.
NCT01132222
/ CompletedPhase 1
A Randomized, Open Label, 2-treatment, Single Dose, Crossover, Bioequivalence Study of Ibuprofen 200 mg+Pseudoephedrine HCL 30 mg Tablets of Dr. Reddy's and Advil® Cold and Sinus Caplets of Wyeth Consumer Healthcare Under Fed Conditions.
100 Clinical Results associated with Ibuprofen/Pseudoephedrine Hydrochloride
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100 Translational Medicine associated with Ibuprofen/Pseudoephedrine Hydrochloride
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100 Patents (Medical) associated with Ibuprofen/Pseudoephedrine Hydrochloride
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100 Deals associated with Ibuprofen/Pseudoephedrine Hydrochloride
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External Link

KEGGWikiATCDrug Bank
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R05X
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Rhinitis, Allergic
Australia
Johnson & Johnson Pacific Pty Ltd.Johnson & Johnson Pacific Pty Ltd.
14 Sep 2001
Sinusitis
Australia
Johnson & Johnson Pacific Pty Ltd.Johnson & Johnson Pacific Pty Ltd.
14 Sep 2001
Nasal Obstruction
China
Hebei Jiheng (Group) Pharmaceutical Co. Ltd.Hebei Jiheng (Group) Pharmaceutical Co. Ltd.
01 Jan 1999
Common Cold
United States
Haleon US Capital LLC
19 Sep 1989
Influenza, Human
United States
Haleon US Capital LLC
19 Sep 1989
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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