Last update 01 Nov 2024

CD3/CD19 negative allogeneic hematopoietic stem cells(University of Pittsburgh)

Overview

Basic Info

Drug Type
Hematopoietic stem cell therapy
Synonyms-
Target
CD19 x CD3
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators), CD3 modulators(T cell surface glycoprotein CD3 modulators), Stem cell replacements
Therapeutic Areas
Immune System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Common Variable ImmunodeficiencyGranulomatous Disease, ChronicHyper-IgM Immunodeficiency Syndrome+ [5]
Inactive Indication-
Originator Organization
University of PittsburghUniversity of Pittsburgh
Active Organization
University of PittsburghUniversity of Pittsburgh
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CD3/CD19 negative allogeneic hematopoietic stem cells(University of Pittsburgh)
NCT01852370 / Enrolling by invitationPhase 1/2IIT
Bilateral Orthotopic Lung Transplant in Tandem With CD3+ and CD19+ Cell Depleted Bone Marrow Transplant From Partially HLA-Matched Cadaveric Donors
100 Clinical Results associated with CD3/CD19 negative allogeneic hematopoietic stem cells(University of Pittsburgh)
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100 Translational Medicine associated with CD3/CD19 negative allogeneic hematopoietic stem cells(University of Pittsburgh)
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100 Patents (Medical) associated with CD3/CD19 negative allogeneic hematopoietic stem cells(University of Pittsburgh)
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100 Deals associated with CD3/CD19 negative allogeneic hematopoietic stem cells(University of Pittsburgh)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Common Variable ImmunodeficiencyPhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
Granulomatous Disease, ChronicPhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
Hyper-IgM Immunodeficiency SyndromePhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
Job SyndromePhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
Mendelian susceptibility to mycobacterial diseasePhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
Neutropenia, Severe ChronicPhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
Wiskott-Aldrich SyndromePhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
ZAP70 DeficiencyPhase 2
US
University of PittsburghUniversity of Pittsburgh
20 Jun 2013
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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