Last update 14 Feb 2026

Recombinant Interleukin 21(ZymoGenetics)

Overview

Basic Info

Drug Type
Interleukins
Synonyms-
Target
IL-21R
Action
agonists
Mechanism
IL-21R agonists(Interleukin 21 Receptor agonists), Cell replacements
Therapeutic Areas
NeoplasmsUrogenital Diseases
Active Indication-
Inactive Indication
Metastatic Renal Cell Carcinoma
Originator Organization
ZymoGenetics, Inc.ZymoGenetics, Inc.
Active Organization-
Inactive Organization
ZymoGenetics, Inc.ZymoGenetics, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Recombinant Interleukin 21(ZymoGenetics)
NCT00389285
/ CompletedPhase 1/2
A Phase 1/2, Open-Label, Dose Escalation Study to Assess the Safety and Pharmacokinetics of Recombinant Interleukin 21 (rIL-21) Administered Concomitantly With Sorafenib (Nexavar) in Subjects With Metastatic Renal Cell Carcinoma
100 Clinical Results associated with Recombinant Interleukin 21(ZymoGenetics)
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100 Translational Medicine associated with Recombinant Interleukin 21(ZymoGenetics)
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100 Patents (Medical) associated with Recombinant Interleukin 21(ZymoGenetics)
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100 Deals associated with Recombinant Interleukin 21(ZymoGenetics)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Renal Cell CarcinomaPhase 2
United States
ZymoGenetics, Inc.ZymoGenetics, Inc.
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
ASCO2008
Phase 1
Indolent Non-Hodgkin Lymphoma
15
efjfugaxqs(yatiluvhbp) = flu-like symptoms, headache, and fatigue efanivdlzy (oxooaxhagd )
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-
20 May 2008
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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