Last update 11 Nov 2024

AGS-8M4

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
AGS 8M4, ASP 6183, ASP-6183
Target
AGS8
Mechanism
AGS8 inhibitors(Fibronectin type III domain protein inhibitors), Surface antigens inhibitors
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseUrogenital Diseases
Active Indication-
Inactive Indication
CarcinomaOvarian CancerPlatinum-Resistant Ovarian Carcinoma
Originator Organization
Agensys, Inc.Agensys, Inc.
Active Organization-
Inactive Organization
Astellas Pharma, Inc.Astellas Pharma, Inc.Agensys, Inc.Agensys, Inc.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with AGS-8M4
NCT01016054 / TerminatedPhase 1
A Phase 1b, Parallel Arm, Multicenter, Open-Label Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Two Different Chemotherapy Regimens in Women With Platinum Resistant or Platinum Sensitive Ovarian Cancer
NCT00816764 / CompletedPhase 1
A Phase 1, Open-label, Multi-center, Dose Escalation Study of the Safety and Pharmacokinetics of AGS-8M4 Given as Monotherapy in Subjects With Advanced Ovarian Cancer
100 Clinical Results associated with AGS-8M4
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100 Translational Medicine associated with AGS-8M4
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100 Patents (Medical) associated with AGS-8M4
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100 Deals associated with AGS-8M4
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ovarian CancerPhase 2-
Agensys, Inc.Agensys, Inc.
-
Platinum-Resistant Ovarian CarcinomaPhase 1
US
Astellas Pharma, Inc.Astellas Pharma, Inc.
01 Oct 2009
CarcinomaPhase 1
US
Astellas Pharma, Inc.Astellas Pharma, Inc.
01 Oct 2008
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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