Last update 21 Nov 2024

AGS-8M4

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
AGS8
Mechanism
AGS8 inhibitors(Fibronectin type III domain protein inhibitors), Surface antigens inhibitors
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseUrogenital Diseases
Active Indication-
Inactive Indication
CarcinomaOvarian CancerPlatinum-Resistant Ovarian Carcinoma
Originator Organization
Agensys, Inc.Agensys, Inc.
Active Organization-
Inactive Organization
Astellas Pharma, Inc.Astellas Pharma, Inc.Agensys, Inc.Agensys, Inc.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with AGS-8M4
NCT01016054 / TerminatedPhase 1
A Phase 1b, Parallel Arm, Multicenter, Open-Label Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Two Different Chemotherapy Regimens in Women With Platinum Resistant or Platinum Sensitive Ovarian Cancer
NCT00816764 / CompletedPhase 1
A Phase 1, Open-label, Multi-center, Dose Escalation Study of the Safety and Pharmacokinetics of AGS-8M4 Given as Monotherapy in Subjects With Advanced Ovarian Cancer
100 Clinical Results associated with AGS-8M4
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100 Translational Medicine associated with AGS-8M4
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100 Patents (Medical) associated with AGS-8M4
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100 Deals associated with AGS-8M4
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Platinum-Resistant Ovarian CarcinomaPhase 2
US
Astellas Pharma, Inc.Astellas Pharma, Inc.
01 Oct 2009
CarcinomaPhase 2
US
Astellas Pharma, Inc.Astellas Pharma, Inc.
01 Oct 2008
Ovarian CancerPhase 2-
Agensys, Inc.Agensys, Inc.
-
Ovarian CancerPhase 2-
Agensys, Inc.Agensys, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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