Last update 20 Mar 2025

CG1/A2xCD3

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms-
Target
CD3 x CTSG x HLA-A2
Action
stimulants, inhibitors
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), CTSG inhibitors(Cathepsin G inhibitors), HLA-A2 inhibitors(HLA-A2 inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid Leukemia
Inactive Indication-
Originator Organization
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer CenterCrossbow Therapeutics, Inc.Crossbow Therapeutics, Inc.Startup
Active Organization
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer CenterCrossbow Therapeutics, Inc.Crossbow Therapeutics, Inc.Startup
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CG1/A2xCD3
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100 Translational Medicine associated with CG1/A2xCD3
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100 Patents (Medical) associated with CG1/A2xCD3
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1
Literatures (Medical) associated with CG1/A2xCD3
Leukemia
Immunotherapy targeting a leader sequence cathepsin G-derived peptide
100 Deals associated with CG1/A2xCD3
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical
United States
Crossbow Therapeutics, Inc.Crossbow Therapeutics, Inc.Startup
12 Feb 2025
Acute Myeloid LeukemiaPreclinical
United States
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer Center
12 Feb 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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