Last update 20 Mar 2025

Chlorpheniramine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Chlorphenamine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride, Ibuprofen/Pseudoephedrine Hydrochloride/Chlorphenamine Maleate, 马来酸氯苯那敏/布洛芬/盐酸伪麻黄碱
+ [1]
Target
COXs x H1 receptor x α-adrenergic receptor
Action
inhibitors, antagonists, agonists
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), H1 receptor antagonists(Histamine H1 receptor antagonists), α-adrenergic receptor agonists(Alpha adrenergic receptor agonists)
Therapeutic Areas
Immune System DiseasesInfectious DiseasesOtorhinolaryngologic Diseases+ [1]
Active Indication
HypersensitivityCommon ColdRhinitis, Allergic, Seasonal+ [1]
Inactive Indication
Influenza, Human
Originator Organization
Pfizer Inc.Pfizer Inc.
Active Organization
Haleon US Capital LLC
Inactive Organization
Pfizer Inc.Pfizer Inc.
Drug Highest PhaseApproved
First Approval Date
United States (19 Dec 2002),
Common ColdRhinitis, Allergic, SeasonalUpper respiratory tract allergy
Regulation-
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Structure/Sequence

Molecular FormulaC13H18O2
InChIKeyHEFNNWSXXWATRW-UHFFFAOYSA-N
CAS Registry15687-27-1
View All Structures (3)

Related

1
Clinical Trials associated with Chlorpheniramine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride
NCT01938144
/ WithdrawnPhase 3
Three-day Clinical Evaluation Of The Efficacy And Safety Of Two Ibuprofen Combination Products For The Symptomatic Treatment Of The Common Cold And Flu: A Multicenter Study
100 Clinical Results associated with Chlorpheniramine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride
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100 Translational Medicine associated with Chlorpheniramine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride
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100 Patents (Medical) associated with Chlorpheniramine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride
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100 Deals associated with Chlorpheniramine Maleate/Ibuprofen/Pseudoephedrine Hydrochloride
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External Link

KEGGWikiATCDrug Bank
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R06AB54R01BA52M01AE51
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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Hypersensitivity
United States
Haleon US Capital LLC
24 Feb 2004
Common Cold
United States
Haleon US Capital LLC
19 Dec 2002
Rhinitis, Allergic, Seasonal
United States
Haleon US Capital LLC
19 Dec 2002
Upper respiratory tract allergy
United States
Haleon US Capital LLC
19 Dec 2002
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Common ColdPhase 3-
Pfizer Inc.Pfizer Inc.
01 Apr 2016
Influenza, HumanPhase 3-
Pfizer Inc.Pfizer Inc.
01 Apr 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Approval

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Regulation

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