Last update 09 Jun 2026

ADR-002

Overview

Basic Info

Drug Type
Gene therapy
Synonyms
Mesenchymal stem cell(Rohto Pharmaceutical), ADR 002, ADR-002
+ [1]
Target-
Action-
Mechanism
Cell replacements
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Chronic heart failureMyocardial Ischemia
Inactive Indication
Ischemic cardiomyopathy
Originator Organization
Osaka University HospitalOsaka University HospitalRohto Pharmaceutical Co., Ltd.Rohto Pharmaceutical Co., Ltd.
Active Organization
Rohto Pharmaceutical Co., Ltd.Rohto Pharmaceutical Co., Ltd.
Inactive Organization
Osaka University HospitalOsaka University Hospital
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

5
Clinical Trials associated with ADR-002
NCT07192211
/ RecruitingPhase 2
Exploratory Study of ADR-002K for Heart Failure Patients With Ischemic Heart Disease Who Undergo Coronary Artery Bypass Surgery
JPRN-jRCT2053250022
/ SuspendedPhase 2IIT
Exploratory Study of ADR-002K for Heart Failure Patients with Ischemic Heart Disease who Undergo Coronary Artery Bypass Surgery
JPRN-jRCT2053190103
/ Not yet recruitingPhase 1IIT
Phase I trial of ADR-002K for patients with ischemic cardiomyopathy who undergo coronary artery bypass surgery
100 Clinical Results associated with ADR-002
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100 Translational Medicine associated with ADR-002
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100 Patents (Medical) associated with ADR-002
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100 Deals associated with ADR-002
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic heart failurePhase 2
Japan
Rohto Pharmaceutical Co., Ltd.Rohto Pharmaceutical Co., Ltd.
28 Apr 2026
Myocardial IschemiaPhase 2
Japan
Rohto Pharmaceutical Co., Ltd.Rohto Pharmaceutical Co., Ltd.
28 Apr 2026
Ischemic cardiomyopathyPhase 1
Japan
Osaka University HospitalOsaka University Hospital
01 Nov 2019
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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