Last update 22 Oct 2026

RO-7568282

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RO-7568282
Target
NLRP3
Action
inhibitors
Mechanism
NLRP3 inhibitors(NACHT, LRR and PYD domains-containing protein 3 inhibitors)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic Disease
Active Indication
Alzheimer DiseasePrimary Parkinson's diseaseParkinson Disease
Inactive Indication-
Originator Organization
F. Hoffmann-La Roche Ltd.F. Hoffmann-La Roche Ltd.
Active Organization
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.F. Hoffmann-La Roche Ltd.F. Hoffmann-La Roche Ltd.Roche R & D Center China Co. Ltd.Roche R & D Center China Co. Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with RO-7568282
NCT07781657
/ Not yet recruitingPhase 2
A Phase II, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of RO7568282 in Participants With Early Symptomatic Alzheimer's Disease
NCT07781644
/ Not yet recruitingPhase 1/2
A Phase II, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of RO7568282 in Participants With Early-stage Parkinson's Disease
CTIS2024-511110-21-00
/ RecruitingPhase 1
A study to test the biological properties of RO7568282 and whether it is safe in healthy participants and participants with Parkinson’s disease.
100 Clinical Results associated with RO-7568282
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100 Translational Medicine associated with RO-7568282
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100 Patents (Medical) associated with RO-7568282
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100 Deals associated with RO-7568282
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePhase 2
United States
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
31 Oct 2026
Parkinson DiseasePhase 2
United Kingdom
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Sep 2026
Primary Parkinson's diseasePhase 2
United States
Roche R & D Center China Co. Ltd.Roche R & D Center China Co. Ltd.
20 Sep 2026
Primary Parkinson's diseasePhase 2
China
Roche R & D Center China Co. Ltd.Roche R & D Center China Co. Ltd.
20 Sep 2026
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Clinical Result

Indication
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Clinical Trial

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Approval

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Regulation

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